Collagen is a tough, glue-like protein that makes up 30% of body protein. It shapes the structure of tendons, bones, and connective tissues. Problems with the immune system can affect these structures. This is known as collagen vascular disease.

Collagen vascular diseases include:

• Dermatomyositis
• Polyarteritis nodosa
• Rheumatoid arthritis
• Scleroderma
• Systemic lupus erythematosus

Symptoms

Symptoms of collagen vascular disease may include:

• Anemia
• Fever
• Joint inflammation
• Weakness