Adult Still's disease is a rare illness marked by high fevers, rash, and joint pain. It may lead to long-term (chronic) arthritis.
It is more commonly called adult-onset Still's disease (AOSD).
Fewer than 1 out of 100,000 people develop adult Still's disease each year. It affects women more often than men.
Still's disease that occurs in children is called systemic juvenile idiopathic arthritis.
The cause of adult Still's disease is unknown. No risk factors for the disease have been identified.
Almost all patients will have fever, joint pain, sore throat, and a rash.
Additional symptoms include:
Occasionally, the spleen or liver may become swollen. Lung and heart inflammation may occur.
Adult Still's disease can only be diagnosed after other diseases are ruled out. You may need many medical tests before a final diagnosis is made.
A physical exam may reveal a fever, rash, and arthritis. The health care provider will use a stethoscope to listen for changes in the sound of the heart or lungs.
The following blood tests can be helpful in diagnosing adult Still's disease.
Other tests may be needed to check for inflammation of the joints, chest, liver, and spleen.
The goal of treatment for adult Still's disease is to control the symptoms of arthritis. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are usually the first form of treatment.
Prednisone may be used for more severe cases.
If the disease persists for a long time (becomes chronic), medicines that suppress the immune system might be needed. Such medicines include:
Studies show that in about 20% of patients, all symptoms go away in a year and never come back. In about 30% of patients, all symptoms go away but then come back several times over the next years.
Symptoms continue for a long-time (chronic) in about half of patients with adult Still's disease.
Call your health care provider if you have symptoms of adult Still's disease.
If you have already been diagnosed with the condition, you should call your health care provider if you have a cough or difficulty breathing.
Still's disease - adult; AOSD