A synovial biopsy is the removal of a piece of tissue lining a joint. The tissue is called the synovial membrane.
The test is usually done in the operating room with the use of arthroscopy.
The health care provider will inject a numbing medicine (local anesthetic) into the area. An instrument called a trocar is inserted into the joint space. This tool helps push fluid in and out of the area. A biopsy grasper is inserted through the trocar and turned to cut out a tissue segment.
The tools are removed. The biopsy site is cleaned. Pressure and a bandage are applied.
Tell your health care provider:
With the local anesthetic, you will feel a prick and a burning sensation. As the trocar is inserted, there will be some discomfort.
Synovial biopsy helps diagnose gout, bacterial infections, or other infections, and may suggest the presence of inflammatory conditions such as autoimmune disorders.
The synovial membrane structure is normal.
Synovial biopsy may identify the following conditions:
The test may help diagnose rheumatoid arthritis and other autoimmune diseases.
There is a very slight chance of infection and bleeding. Rarely, there is a chance of the needle striking a nerve or blood vessel.
Biopsy - synovial membrane