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Drugs reference index «Fosamprenavir Suspension»

Fosamprenavir Suspension

Generic Name: Fosamprenavir (FOS-am-PREN-a-vir)Brand Name: Lexiva

Fosamprenavir Suspension is used for:

Treating HIV infection in some patients when used in combination with certain other medicines.

Fosamprenavir Suspension is an HIV protease inhibitor. It works by slowing the growth of HIV, the virus that causes AIDS.

Do NOT use Fosamprenavir Suspension if:

  • you are allergic to any ingredient in Fosamprenavir Suspension or to amprenavir
  • you are taking amprenavir, cisapride, conivaptan, delavirdine, erythromycin, an ergot medicine (eg, ergotamine), an H1 antagonist (eg, astemizole, terfenadine), pimozide, rifampin, or St. John's wort
  • you are taking a hormonal contraceptive (eg, birth control pills), certain benzodiazepines (eg, midazolam, triazolam), or certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin)
  • you are taking flecainide or propafenone along with ritonavir

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fosamprenavir Suspension:

Some medical conditions may interact with Fosamprenavir Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, a severe rash, hives, itching, breathing difficulties, or dizziness) to a sulfonamide medicine such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
  • if you have liver problems, hepatitis, or a history of abnormal liver function tests
  • if you have a history of heart problems, high blood pressure, kidney problems, diabetes, bleeding problems (eg, hemophilia), high blood cholesterol or lipid levels, or a skin rash
  • if you smoke

Some MEDICINES MAY INTERACT with Fosamprenavir Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cisapride, an ergot medicine (eg, ergotamine), erythromycin, H1 antagonists (eg, astemizole, terfenadine), or pimozide because serious side effects, such as seizures, blood vessel problems, or heart problems (eg, irregular heartbeat), may occur
  • Flecainide or propafenone along with ritonavir because serious heart problems (eg, irregular heartbeat) may occur
  • Certain benzodiazepines (eg, midazolam, triazolam) because serious side effects, such as increased or prolonged sedation or breathing problems, may occur
  • Hormonal contraceptives (eg, birth control pills), especially if taken along with ritonavir, because their effectiveness may be decreased and liver problems may occur
  • Amprenavir because it may increase the risk of Fosamprenavir Suspension's side effects
  • Rifampin or St. John's wort because they may decrease Fosamprenavir Suspension's effectiveness
  • Conivaptan, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), or ranolazine because the risk of their side effects may be increased by Fosamprenavir Suspension
  • Delavirdine because its effectiveness may be decreased by Fosamprenavir Suspension
  • Many prescription and nonprescription medicines (eg, used for cancer, infections, asthma, immune suppression, inflammation, aches and pains, high blood pressure, high cholesterol, heart problems, irregular heartbeat, angina, blood clotting problems, mood or mental problems, sinus problems, stomach problems or indigestion, erectile dysfunction, seizures, sleeping problems, urinary problems, HIV infection), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo) may interact with Fosamprenavir Suspension, increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fosamprenavir Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fosamprenavir Suspension:

Use Fosamprenavir Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Fosamprenavir Suspension. Talk to your pharmacist if you have questions about this information.
  • Adults should take Fosamprenavir Suspension by mouth without food.
  • Children should take Fosamprenavir Suspension by mouth with food. If vomiting occurs within 30 minutes after taking Fosamprenavir Suspension, the dose should be taken again.
  • Shake well before each use.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • You may refrigerate Fosamprenavir Suspension to help improve the taste. Do not freeze.
  • Eating grapefruit or drinking grapefruit juice while you are taking Fosamprenavir Suspension may increase the amount of Fosamprenavir Suspension in your blood. This may increase your risk for serious side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
  • If you take an aluminum- or magnesium-containing antacid, ask your doctor or pharmacist how to take it with Fosamprenavir Suspension.
  • Do not change your dose or stop taking Fosamprenavir Suspension without talking with your doctor first. Continue to take Fosamprenavir Suspension even if you feel well. Do not miss any doses.
  • Taking Fosamprenavir Suspension at the same time(s) each day will help you remember to take it. It is important to not miss any doses of Fosamprenavir Suspension.
  • If you miss a dose of Fosamprenavir Suspension, take it as soon as you remember. If you miss a dose of Fosamprenavir Suspension by more than 4 hours, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Fosamprenavir Suspension.

Important safety information:

  • Do not take more than the recommended dose without checking with your doctor.
  • Fosamprenavir Suspension is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
  • Fosamprenavir Suspension does not stop the spread of HIV to others through blood or sexual contact. Use barrier forms of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
  • When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Fosamprenavir Suspension, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
  • Fosamprenavir Suspension may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice signs or symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Fosamprenavir Suspension.
  • Severe and sometimes life-threatening skin reactions have occurred in patients taking Fosamprenavir Suspension. Contact your doctor right away if you develop any type of skin reaction (eg, red, swollen, blistered, or peeling skin).
  • Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Fosamprenavir Suspension. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.
  • Diabetes patients - Fosamprenavir Suspension may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Fosamprenavir Suspension may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Fosamprenavir Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Lab tests, including liver function, cholesterol or triglyceride levels, white blood cell count, and blood sugar levels, may be performed while you use Fosamprenavir Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Caution is advised when using Fosamprenavir Suspension in CHILDREN; they may be more sensitive to its effects, especially vomiting.
  • Fosamprenavir Suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fosamprenavir Suspension while you are pregnant. It is not known if Fosamprenavir Suspension is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Fosamprenavir Suspension to the baby.

Possible side effects of Fosamprenavir Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; nausea; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); loss of appetite; signs of infection (eg, fever, chills, sore throat); swollen, reddened, or blistered skin; symptoms of a heart attack (eg, chest pain; fainting; numbness of an arm or leg; sudden, severe headache or vomiting); symptoms of kidney stones (eg, lower back or side pain, blood in the urine, painful urination); unusual increase in thirst or urination; unusual tiredness or weakness; weight loss; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Fosamprenavir Suspension:

Store Fosamprenavir Suspension in the refrigerator or at room temperature, between 41 and 86 degrees F (5 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep the container tightly closed. Do not use after the expiration date. Keep Fosamprenavir Suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about Fosamprenavir Suspension, please talk with your doctor, pharmacist, or other health care provider.
  • Fosamprenavir Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fosamprenavir Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • fosamprenavir Advanced Consumer (Micromedex) - Includes Dosage Information
  • Lexiva Prescribing Information (FDA)
  • Lexiva Detailed Consumer Information (PDR)
  • Lexiva Consumer Overview

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