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Drugs reference index «Glumetza»



Generic name: Metformin hydrochlorideBrand names: Glumetza

Why is Glumetza prescribed?

Glumetza is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Most important fact about Glumetza

Glumetza can cause a rare, but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in the hospital. Stop taking Glumetza and call your doctor right away if you: feel very weak or tired, have muscle pain, have trouble breathing, have stomach pain with nausea and vomiting, or diarrhea, feel cold, especially in your arms and legs, feel dizzy or lightheaded, have a slow or irregular heartbeat, or if a medical condition suddenly changes.

You have a higher chance for getting lactic acidosis with Glumetza if you have kidney or liver problems, have congestive heart failure that requires treatments with medicines, drink a lot of alcohol, get dehydrated (lose a large amount of body fluids). Dehydration can happen if you are sick with a fever, have diarrhea, or from vomiting. Dehydration can also happen when you sweat a lot with activity or exercise and don't drink enough fluids.

How should you take Glumetza?

Take Glumetza once a day in the evening with food. Swallow tablets whole. Never crush or chew Glumetza tablets.

  • Storage instructions...Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Glumetza.

  • Side effects may include:Diarrhea, nausea, upset stomach

These side effects usually go away after you take the medicine for a while. Taking your medicine with the evening meal can help reduce these side effects. Also, it is perfectly normal to see the Glumetza tablet shell in your stool.

Why should Glumetza not be prescribed?

Do not take Glumetza if you have kidney problems, heart failure, are allergic to Glumetza or to any of its ingredients, or have a condition called metabolic acidosis, including diabetic ketoacidosis. Diabetic ketoacidosis should be treated with insulin.

Special warnings about Glumetza

Do not drink a lot of alcoholic drinks while taking Glumetza. This means you should not binge drink for short periods, and you should not drink a lot of alcohol on a regular basis. Alcohol can increase the chance of getting lactic acidosis.

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Glumetza. Also, talk to your doctor about your complete medical history, especially if you have kidney, liver or heart problems, drink a lot of alcohol, or if you are pregnant, planning to become pregnant or are nursing.

Special information if you are pregnant or breastfeeding

Treatment with Glumetza is not recommended during pregnancy or breastfeeding. If you are pregnant, planning to become pregnant, or are nursing, talk to your doctor about your therapy options.

Recommended dosage for Glumetza


The usual starting dose of Glumetza is 1,000 milligrams (mg) a day, taken with food in the evening. Dosage increases should be made in increments of 500 mg a week, up to a maximum of 2,000 mg once-a-day with the evening meal.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

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