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Drugs reference index «Grifulvin V»

Grifulvin V

Generic Name: griseofulvin (Oral route)

gris-ee-oh-FUL-vin

Commonly used brand name(s):

In the U.S.

  • Fulvicin P/G
  • Fulvicin-U/F
  • Grifulvin V
  • Gris-PEG

Available Dosage Forms:

  • Tablet
  • Capsule
  • Suspension

Therapeutic Class: Antifungal

Uses For Grifulvin V

Griseofulvin belongs to the group of medicines called antifungals. It is used to treat fungus infections of the skin, hair, fingernails, and toenails. This medicine may be taken alone or used along with medicines that are applied to the skin for fungus infections.

Griseofulvin is available only with your doctor's prescription.

Before Using Grifulvin V

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in a limited number of children 2 years of age or older. In effective doses, the medicine has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of griseofulvin in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Desogestrel
  • Ethinyl Estradiol
  • Etonogestrel
  • Levonorgestrel
  • Mestranol
  • Norelgestromin
  • Norethindrone
  • Norgestrel
  • Phenobarbital
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Liver disease—Griseofulvin may on rare occasion cause side effects affecting the liver
  • Lupus erythematosus or lupus-like diseases—Griseofulvin may worsen lupus symptoms in patients who have lupus erythematosus or lupus-like diseases
  • Porphyria—Griseofulvin may increase attacks of porphyria in patients with acute intermittent porphyria

Proper Use of griseofulvin

This section provides information on the proper use of a number of products that contain griseofulvin. It may not be specific to Grifulvin V. Please read with care.

Griseofulvin is absorbed best when it is taken with a high fat meal, such as a cheeseburger, whole milk, or ice cream. Tell your doctor if you are on a low-fat diet.

Griseofulvin is best taken with or after meals, especially fatty ones (for example, whole milk or ice cream). This lessens possible stomach upset and helps to clear up the infection by helping your body absorb the medicine better. However, if you are on a low-fat diet, check with your doctor.

For patients taking the oral liquid form of griseofulvin :

  • Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For microsize capsules, tablets, and suspension:
    • Adults and teenagers:
      • Treatment of fungus infections of the feet and nails—500 milligrams (mg) every twelve hours.
      • Treatment of fungus infections of the scalp, skin, and groin—250 mg every twelve hours; or 500 mg once a day.
    • Children:
      • Treatment of fungus infections—Dose is based on body weight. The usual dose is 5 mg per kilogram (kg) (2.3 mg per pound) of body weight every twelve hours; or 10 mg per kg (4.6 mg per pound) of body weight once a day.
  • For ultramicrosize tablets:
    • Adults and teenagers:
      • Treatment of fungus infections of the feet and nails—250 to 375 mg every twelve hours.
      • Treatment of fungus infections of the scalp, skin, and groin—125 to 187.5 mg every twelve hours; or 250 to 375 mg once a day.
    • Infants and children up to 2 years of age:
      • Treatment of fungus infections—Use and dose must be determined by your doctor.
    • Children 2 years of age and over:
      • Treatment of fungus infections—Dose is based on body weight. The usual dose is 2.75 to 3.65 mg per kg (1.25 to 1.7 mg per pound) of body weight every twelve hours; or 5.5 to 7.3 mg per kg (2.5 to 3.3 mg per pound) of body weight once a day.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Grifulvin V

Your doctor should check your progress at regular visits to make sure that griseofulvin does not cause unwanted effects.

Oral contraceptives (birth control pills) containing estrogen may not work properly if you take them while you are taking griseofulvin. Unplanned pregnancies may occur. You should use a different or additional means of birth control while you are taking griseofulvin and for one month after stopping griseofulvin. If you have any questions about this, check with your health care professional.

Griseofulvin may increase the effects of alcohol. If taken with alcohol it may also cause fast heartbeat, flushing, increased sweating, or redness of the face. Therefore, if you have this reaction, do not drink alcoholic beverages while you are taking this medicine, unless you have first checked with your doctor.

This medicine may cause some people to become dizzy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do other things that could be dangerous if you are dizzy or are not alert. If these reactions are especially bothersome, check with your doctor.

Griseofulvin may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:

  • Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
  • Wear protective clothing, including a hat. Also, wear sunglasses.
  • Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.
  • Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.
  • Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor.

Grifulvin V Side Effects

Griseofulvin has been shown to cause liver and thyroid tumors in some animals. You and your doctor should discuss the good this medicine will do, as well as the risks of taking it.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common
  • Confusion
  • increased sensitivity of skin to sunlight
  • skin rash, hives, or itching
  • soreness or irritation of mouth or tongue
Rare
  • Numbness, tingling, pain, or weakness in hands or feet
  • sore throat and fever
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Headache
Less common
  • Diarrhea
  • dizziness
  • nausea or vomiting
  • stomach pain
  • trouble in sleeping
  • unusual tiredness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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  • Grifulvin V Microsize MedFacts Consumer Leaflet (Wolters Kluwer)
  • Grifulvin V Concise Consumer Information (Cerner Multum)
  • Griseofulvin Prescribing Information (FDA)
  • Griseofulvin Professional Patient Advice (Wolters Kluwer)
  • Fulvicin P/G Detailed Consumer Information (PDR)
  • Gris-PEG Ultramicrosize Tablets MedFacts Consumer Leaflet (Wolters Kluwer)
  • Gris-PEG Prescribing Information (FDA)

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