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Drugs reference index «Ilaris»

Ilaris

Generic Name: Canakinumab (KAN-a-KIN-ue-mab)Brand Name: Ilaris

Ilaris is used for:

Treating certain auto-inflammatory diseases known as cryopyrin-associated periodic syndrome (CAPS), including familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS). It may also be used for other conditions as determined by your doctor.

Ilaris is an interleukin-1 beta-blocker. It works by decreasing the activity of a protein called interleukin-1 beta, which may help to decrease inflammation.

Do NOT use Ilaris if:

  • you are allergic to any ingredient in Ilaris
  • you are using another interleukin-1 blocker (eg, anakinra) or a tumor necrosis factor (TNF) blocker (eg, adalimumab)
  • you will be receiving a live vaccine
  • you have a severe infection (eg, sepsis), HIV, hepatitis B or C, or any other active infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ilaris :

Some medical conditions may interact with Ilaris . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances, including rubber
  • if you have a history of an infection that keeps coming back, a tuberculosis (TB) infection or positive TB skin test, hepatitis B infection, or cancer
  • if you have an autoimmune disorder (eg, lupus) or other immune system problems, have recently received a vaccine, are scheduled to receive a vaccine, or are scheduled to have surgery
  • if you have open cuts or sores on your body or flu-like symptoms or other signs of infection (eg, fever; chills; cough; warm, red, or painful skin), or if you are using medicine to treat an infection
  • if you have ever lived in or traveled to an area where TB is common, or if you have come into close contact with a person with active TB
  • if you take medicine that may decrease your immune system (eg, cyclosporine)

Some MEDICINES MAY INTERACT with Ilaris . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Another interleukin-1 blocker (eg, anakinra) or a tumor necrosis factor (TNF) blocker (eg, adalimumab) because the risk of serious infection may be increased
  • Warfarin because the risk of its side effects may be increased by Ilaris

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ilaris may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ilaris :

Use Ilaris as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Ilaris . Talk to your pharmacist if you have questions about this information.
  • Ilaris is given as an injection under the skin at your doctor's office, hospital, or clinic.
  • Ilaris is usually used every 8 weeks. Do not use more often than every 8 weeks unless your doctor tells you otherwise.
  • If you miss a dose of Ilaris , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Ilaris .

Important safety information:

  • Ilaris may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ilaris with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Ilaris may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • The safety of Ilaris in patients with inactive TB has not been confirmed. You may need to have a TB skin test before you start Ilaris to determine if you have TB infection. Discuss any questions or concerns with your doctor.
  • Medicines that suppress the immune system, including Ilaris , may increase the risk of developing certain types of cancer. Talk with your doctor if you have questions or concerns.
  • Tell your doctor or dentist that you take Ilaris before you receive any medical or dental care, emergency care, or surgery.
  • It is recommended that your vaccines be up to date before you begin Ilaris . Check with your doctor if you have any questions.
  • Do not receive a live vaccine (eg, measles, mumps) while you are taking Ilaris . Talk with your doctor before you receive any vaccine.
  • Ilaris should not be used in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ilaris while you are pregnant. It is not known if Ilaris is found in breast milk. If you are or will be breast-feeding while you use Ilaris , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ilaris :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cold or flu symptoms; diarrhea; dizziness; headache; mild pain, redness, or swelling at the injection site; mild sore throat; nausea; sinus inflammation; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; open sore that does not heal; persistent cough; persistent pain, swelling, or redness at the injection site; severe or persistent headache or dizziness; signs of infection (eg, fever, chills, or sore throat; warm, red, or painful skin; increased or painful urination); unusual bruising; unusual lumps; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Ilaris :

Ilaris is usually handled and stored by a health care provider. If you are using Ilaris at home, store Ilaris as directed by your pharmacist or health care provider. Keep Ilaris out of the reach of children and away from pets.

General information:

  • If you have any questions about Ilaris , please talk with your doctor, pharmacist, or other health care provider.
  • Ilaris is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ilaris . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Ilaris Prescribing Information (FDA)
  • Ilaris Advanced Consumer (Micromedex) - Includes Dosage Information
  • Ilaris Consumer Overview
  • Canakinumab Professional Patient Advice (Wolters Kluwer)

See Also...

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