Generic name: Propranolol hydrochlorideBrand names: Inderal LA, Inderal
Inderal, a type of medication known as a beta blocker, is used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), changes in heart rhythm, prevention of migraine headache, hereditary tremors, hypertrophic subaortic stenosis (a condition related to exertional angina), and tumors of the adrenal gland. It is also used to reduce the risk of death from recurring heart attack. InnoPran XL is used to treat high blood pressure.
When Inderal and InnoPran XL are used for the treatment of high blood pressure, they are effective alone or combined with other high blood pressure medications, particularly thiazide-type diuretics. Beta blockers decrease the force and rate of heart contractions, reducing the heart's demand for oxygen and lowering blood pressure.
If you have high blood pressure, you must take Inderal regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Inderal; and you must continue taking it even if you are feeling well. Inderal does not cure high blood pressure; it merely keeps it under control.
Inderal works best when taken before meals. Take it exactly as prescribed, even if your symptoms have disappeared. InnoPran XL should be taken once before bedtime, with or without food.
Try not to miss any doses. If Inderal is not taken regularly, your condition may worsen.
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Inderal.
If you have inadequate blood supply to the circulatory system (cardiogenic shock), certain types of irregular heartbeat, a slow heartbeat, bronchial asthma, or severe congestive heart failure, you should not take Inderal.
If you have a history of congestive heart failure, your doctor will prescribe Inderal cautiously.
Inderal should not be stopped suddenly. This can cause increased chest pain and heart attack. Dosage should be gradually reduced.
If you suffer from asthma or other bronchial conditions, coronary artery disease, or kidney or liver disease, Inderal should be used with caution.
Ask your doctor if you should check your pulse while taking Inderal. This medication can cause your heartbeat to become too slow.
This medication may mask the symptoms of low blood sugar or alter blood sugar levels. In addition, diabetics who experience a severe drop in blood sugar after taking insulin may suffer a spike in blood pressure if they are also taking Inderal.
Notify your doctor or dentist that you are taking Inderal if you have a medical emergency, and before you have surgery or dental treatment.
If Inderal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Inderal with the following:AlcoholAluminum hydroxide gelAntipyrineCalcium-blocking blood pressure drugs such as diltiazem, nifedipine, and verapamilCertain high blood pressure medications such as reserpineChlorpromazineCimetidineEpinephrineHaloperidolInsulinLidocaineNonsteroidal anti-inflammatory drugs such as ibuprofen and naproxenOral diabetes drugs such as glyburidePhenobarbitonePhenytoinRifampinTheophyllineThyroid medications such as levothyroxine
The effects of Inderal during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Inderal appears in breast milk and could affect a nursing infant. If Inderal is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Inderal is finished.
All dosages of Inderal, for any problem, must be tailored to the individual. Your doctor will determine when and how often you should take Inderal. If you are over 65, the doctor will probably start with a relatively low dosage. Remember to take it exactly as directed.
The usual starting dose of Inderal is 40 milligrams 2 times a day. This dose may be in combination with a diuretic. Dosages are gradually increased to between 120 milligrams and 240 milligrams per day for maintenance. In some cases, a dose of 640 milligrams per day may be needed. Depending on the individual, maximum effect of Inderal may not be reached for a few days or even several weeks. Some people may do better taking Inderal 3 times a day.
The usual starting dose of InnoPran XL is 80 milligrams once daily at bedtime. Depending on your response, the doctor may increase your dose to 120 milligrams.
The usual daily dosage is 80 milligrams to 320 milligrams, divided into 2, 3, or 4 smaller doses. When your treatment is being discontinued, your doctor will reduce the dosage gradually over a period of several weeks.
The usual dose is 10 milligrams to 30 milligrams 3 or 4 times a day, before meals and at bedtime.
The usual daily dosage is 180 milligrams to 240 milligrams divided into smaller doses. The usual maximum dose is 240 milligrams, although your doctor may increase the dose when treating heart attack with angina or high blood pressure.
The usual starting dosage is 80 milligrams per day divided into smaller doses. Dosages can be increased gradually to between 160 milligrams and 240 milligrams per day. If this dose does not relieve your symptoms in 4 to 6 weeks, your doctor will slowly take you off the drug.
The usual starting dose is 40 milligrams, 2 times per day. Symptoms will usually be relieved with a dose of 120 milligrams per day; however, on occasion, dosages of 240 milligrams to 320 milligrams per day may be necessary.
Hypertrophic Subaortic Stenosis
The usual dose is 20 milligrams to 40 milligrams, 3 to 4 times a day, before meals and at bedtime.
Before Adrenal Gland Surgery
The usual dose is 60 milligrams a day divided into smaller doses for 3 days before surgery in combination with an alpha-blocker drug.
Inderal may also be taken by people with inoperable tumors in doses of 30 milligrams a day, divided into smaller doses.
Inderal will be carefully individualized for use in children and is used only for high blood pressure. Doses in children are calculated by body weight, and range from 2 milligrams to 4 milligrams per 2.2 pounds daily, divided into 2 equal doses. The maximum dose is 16 milligrams per 2.2 pounds per day.
If treatment is stopped, Inderal must be gradually reduced over a 7- to 14-day period.
Inderal is also available in a sustained-release formulation, called Inderal LA, for once-a-day dosing.
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.