Lamictal XR Extended-Release TabletsGeneric Name: Lamotrigine
Serious and sometimes fatal rashes have rarely occurred with the use of Lamictal XR Extended-Release Tablets. The risk of serious rash may be greater in children younger than 16 years old than in adults. Although it has not been proven, the risk may also be greater if you start taking Lamictal XR Extended-Release Tablets at a higher dose than recommended, if you take more than the recommended dose during treatment, or if you also take a medicine called valproate (eg, valproic acid, divalproex sodium). Most of the serious rashes that have occurred with the use of Lamictal XR Extended-Release Tablets developed within the first 2 to 8 weeks of treatment. However, serious rashes have also occurred in patients who have used Lamictal XR Extended-Release Tablets for a longer period of time. Contact your doctor at once if you develop rash symptoms, including red, swollen, blistered, or peeling skin. Treatment with Lamictal XR Extended-Release Tablets should be stopped if rash occurs, unless it is clearly determined that the medicine did not cause the rash. Even if Lamictal XR Extended-Release Tablets are stopped, a rash caused by Lamictal XR Extended-Release Tablets may still become life-threatening or cause other serious side effects (eg, permanent scarring).
Lamictal XR Extended-Release Tablets are used for:
Treating certain types of seizures in certain patients. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.
Lamictal XR Extended-Release Tablets are an anticonvulsant. Exactly how it works is not known.
Do NOT use Lamictal XR Extended-Release Tablets if:
- you are allergic to any ingredient in Lamictal XR Extended-Release Tablets
Contact your doctor or health care provider right away if any of these apply to you.
Before using Lamictal XR Extended-Release Tablets:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver or kidney problems, heart problems, or certain blood problems (eg, thalassemia), or if you receive dialysis treatment
- if you have a skin rash or have ever developed a skin rash from taking Lamictal XR Extended-Release Tablets or any other medicines to treat seizures
- if you have a history of mental or mood problems (eg, depression, suicidal thoughts or attempts)
Some MEDICINES MAY INTERACT with Lamictal XR Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Carbamazepine because it may decrease Lamictal XR Extended-Release Tablets's effectiveness; the risk of side effects, such as dizziness, double vision, blurred vision, and decreased coordination, may be increased
- Valproate (eg, valproic acid, divalproex sodium) because it may increase the risk of Lamictal XR Extended-Release Tablets's side effects
- Estrogens, phenobarbital, phenytoin, primidone, rifampin, or succinimides (eg, methsuximide) because they may decrease Lamictal XR Extended-Release Tablets's effectiveness
- Hormonal contraceptives (eg, birth control pills) because the effectiveness of both medicines may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Lamictal XR Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Lamictal XR Extended-Release Tablets:
Use Lamictal XR Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Lamictal XR Extended-Release Tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Lamictal XR Extended-Release Tablets refilled.
- Take Lamictal XR Extended-Release Tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Swallow Lamictal XR Extended-Release Tablets whole. Do not break, crush, or chew before swallowing. Some brands of Lamictal XR Extended-Release Tablets may be broken in half before taking. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand of medicine may be broken in half.
- Continue to take Lamictal XR Extended-Release Tablets even if you feel well. Do not miss any doses.
- If you miss a dose of Lamictal XR Extended-Release Tablets, take it as soon as possible. If it is almost time for you next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Lamictal XR Extended-Release Tablets.
Important safety information:
- Lamictal XR Extended-Release Tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Lamictal XR Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Do not suddenly stop taking Lamictal XR Extended-Release Tablets or change your dose without checking with your doctor. Doing so may increase seizure frequency. If you need to stop taking Lamictal XR Extended-Release Tablets, your dose should be gradually reduced over a period of at least 2 weeks.
- If you stop taking Lamictal XR Extended-Release Tablets for any reason, contact your doctor right away. Do not start taking it again unless your doctor tells you to. Discuss any questions or concerns with your doctor.
- If you develop new or worsening seizures, contact your doctor right away.
- Patients who take Lamictal XR Extended-Release Tablets may be at increased risk for suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Patients who have bipolar (manic-depressive) illness may also have an increased risk for suicidal thoughts or actions. Watch patients who take Lamictal XR Extended-Release Tablets closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Hormonal birth control (eg, birth control pills) may change the amount of Lamictal XR Extended-Release Tablets in your blood. Talk to your doctor before you start or stop taking hormonal birth control while you are taking Lamictal XR Extended-Release Tablets. Women who take hormonal birth control may be at greater risk for side effects during the week of inactive pills in their pack. Contact your doctor if side effects, such as dizziness, decreased coordination, or double vision, occur.
- Hormonal birth control (eg, birth control pills) may not work as well while you use Lamictal XR Extended-Release Tablets. Check with your doctor if you have questions about how Lamictal XR Extended-Release Tablets might affect your hormonal birth control. Contact your doctor right away if you notice any unusual vaginal bleeding or spotting. If you wish to avoid pregnancy, talk with your doctor about the use of effective birth control methods.
- Tell your doctor or dentist that you take Lamictal XR Extended-Release Tablets before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including complete blood cell counts, may be performed while you use Lamictal XR Extended-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Different medicines may look like or have names similar to Lamictal XR Extended-Release Tablets. Always check your medicine to make sure it appears correct. If you notice any change in the appearance of your medicine (eg, shape, color, size, wording), check with your pharmacist.
- Caution is advised when using Lamictal XR Extended-Release Tablets in CHILDREN; they may be more sensitive to its effects, especially the risk of serious rash.
- Lamictal XR Extended-Release Tablets should not be used in CHILDREN younger than 13 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Lamictal XR Extended-Release Tablets may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lamictal XR Extended-Release Tablets while you are pregnant. Lamictal XR Extended-Release Tablets are found in breast milk. Do not breast-feed while taking Lamictal XR Extended-Release Tablets.
Possible side effects of Lamictal XR Extended-Release Tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Blurred or double vision; constipation; decreased coordination; diarrhea; dizziness; drowsiness; headache; nausea; painful menstrual periods; runny or stuffy nose; stomach upset or pain; tiredness; trouble sleeping; vomiting; weakness; weight loss.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unexplained hoarseness); absent menstrual period or other menstrual changes; calf pain or tenderness; chest pain; dark urine; difficult or painful urination; fast or irregular heartbeat; fever, chills, or persistent sore throat; new or worsening mental or mood changes (eg, anxiety, depression, restlessness, irritability, panic attacks, behavior changes, suicidal thoughts or attempts); new or worsening seizures; pale stools; reddened, blistered, swollen, or peeling skin; severe muscle pain or tenderness; severe or persistent stomach pain; shortness of breath; sores in the mouth or around the eyes; swelling of the hands, ankles, or feet; swollen lymph glands; tremor; unusual bruising or bleeding; unusual weakness or tiredness; vaginal itching or discharge; vision changes; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; involuntary eye movements; loss of consciousness or coordination; new or worsening seizures.Proper storage of Lamictal XR Extended-Release Tablets:
Store Lamictal XR Extended-Release Tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lamictal XR Extended-Release Tablets out of the reach of children and away from pets.
- If you have any questions about Lamictal XR Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
- Lamictal XR Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Lamictal XR Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Lamictal XR Prescribing Information (FDA)
- Lamictal XR Advanced Consumer (Micromedex) - Includes Dosage Information
- Lamotrigine Prescribing Information (FDA)
- Lamotrigine Professional Patient Advice (Wolters Kluwer)
- Lamictal Detailed Consumer Information (PDR)
- Lamictal Consumer Overview
- Lamictal Prescribing Information (FDA)