Linezolid SuspensionGeneric Name:
Linezolid (lin-AYZ-oh-lid)Brand Name:
Linezolid Suspension is used for:
Treating adults with certain serious bacterial infections that are often resistant to other antibiotics.
Linezolid Suspension is an oxazolidinone antibiotic. It works by interfering with the production of proteins needed by bacteria to grow.
Do NOT use Linezolid Suspension if:
- you are allergic to any ingredient in Linezolid Suspension
- you are taking an amphetamine (eg, dextroamphetamine), certain anorexiants (eg, phentermine), buspirone, a catechol-O-methyltransferase (COMT) inhibitor (eg, entacapone), levodopa, meperidine, a sympathomimetic (eg, albuterol, dopamine, epinephrine, pseudoephedrine), tetrabenazine, or triptans (eg, sumatriptan)
- you are taking or have taken certain anorexiants (eg, sibutramine), apraclonidine, bupropion, cyclobenzaprine, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), a norepinephrine reuptake inhibitor (eg, atomoxetine), a serotonin norepinephrine reuptake inhibitor (eg, duloxetine), a serotonin reuptake inhibitor (eg, paroxetine), a tetracyclic antidepressant (eg, maprotiline), or a tricyclic antidepressant (eg, amitriptyline) within the past 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using Linezolid Suspension:
Some medical conditions may interact with Linezolid Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of high blood pressure, kidney problems, bone marrow problems, low blood cell or platelet levels, an adrenal gland tumor (pheochromocytoma), carcinoid syndrome, severe liver problems, seizures, an overactive thyroid, or phenylketonuria
- if you have a prolonged infection that has been previously treated with another antibiotic medicine
- if you are taking any medicine for depression
Some MEDICINES MAY INTERACT with Linezolid Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Amphetamines (eg, dextroamphetamine), apraclonidine, certain anorexiants (eg, phentermine, sibutramine), ginseng, meperidine, sympathomimetics (eg, albuterol, dopamine, epinephrine, pseudoephedrine), or tryptophan because the risk of serious side effects, including severe headache, fever, or high blood pressure, may be increased
- Bupropion, busporine, COMT inhibitors (eg, entacapone), levodopa, MAOIs (eg, phenelzine), norepinephrine reuptake inhibitors (eg, atomoxetine), propoxyphene, serotonin norepinephrine reuptake inhibitors (eg, duloxetine), tetrabenazine, tetracyclic antidepressants (eg, maprotiline), tricyclic antidepressants (eg, amitriptyline), or triptan (eg, sumatriptan) because the risk of serious side effects, including severe fever, mental or mood changes, or muscle problems, may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Linezolid Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Linezolid Suspension:
Use Linezolid Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Linezolid Suspension by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Gently mix before each dose by turning the bottle upside-down 3 to 5 times. Do not shake Linezolid Suspension.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- To clear up your infection completely, take Linezolid Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.
- If you miss a dose of Linezolid Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Linezolid Suspension.
Important safety information:
- Linezolid Suspension may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Linezolid Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Be sure to use Linezolid Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Long-term or repeated use of Linezolid Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
- Eating foods high in tyramine (eg, aged cheeses, red wines, beer, certain meats and sausages, liver, sour cream, soy sauce, raisins, bananas, avocados) while you use an MAOI may cause severe high blood pressure. This could occur for up to 2 weeks after you stop taking an MAOI. Do not eat foods high in tyramine while you take Linezolid Suspension. Ask your health care provider for a complete list of foods you should avoid. Seek medical attention at once if symptoms of severe high blood pressure occur. These may include severe headache, fast or irregular heartbeat, sore or stiff neck, nausea, vomiting, sweating, enlarged pupils, or sensitivity to light.
- Linezolid Suspension may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Linezolid Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).
- Phenylketonuria patients - Linezolid Suspension contains phenylalanine. If you must have a diet that is low in phenylalanine, talk with your doctor or pharmacist.
- Lab tests, including complete blood cell counts, may be performed while you use Linezolid Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Linezolid Suspension should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Linezolid Suspension while you are pregnant. It is not known if Linezolid Suspension is found in breast milk. If you are or will be breast-feeding while you use Linezolid Suspension, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Linezolid Suspension:
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Bad taste in mouth; constipation; diarrhea; dizziness; headache; nausea; tongue discoloration; trouble sleeping; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; bloody stools; bloody vomit; chills; confusion; exaggerated reflexes; excitation; fast heartbeat; loss of coordination; mental or mood changes; muscle spasms; prolonged or repeated nausea or vomiting; seizures; severe or continuing diarrhea; sore throat or fever; stomach pain/cramps; sweating; swelling of the hands or feet; tingling or numbness of hands or feet; unusual bleeding or bruising; unusual tiredness or weakness; vaginal irritation or unusual discharge; vision changes; white patches in the mouth.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Linezolid Suspension:
Store Linezolid Suspension at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep bottle tightly closed. Discard any unused medicine 21 days after mixing. Keep Linezolid Suspension out of the reach of children and away from pets.
- If you have any questions about Linezolid Suspension, please talk with your doctor, pharmacist, or other health care provider.
- Linezolid Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Linezolid Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Linezolid Professional Patient Advice (Wolters Kluwer)
- Linezolid Detailed Consumer Information (PDR)
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- Zyvox Consumer Overview