Generic Name: lisdexamfetamine (lis dex am FET a meen)Brand Names: Vyvanse
Lisdexamfetamine is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.
Lisdexamfetamine is used to treat attention deficit hyperactivity disorder (ADHD) in adults and in children who are 6 to 12 years old.
Lisdexamfetamine may also be used for other purposes not listed in this medication guide.
Do not use this medication if you are allergic to lisdexamfetamine or if you have:
heart disease or moderate to severe high blood pressure (hypertension);
arteriosclerosis (hardening of the arteries);
severe anxiety, tension, or agitation; or
if you have a history of drug or alcohol addiction.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take lisdexamfetamine:
a congenital heart defect;
high blood pressure;
heart failure, heart rhythm disorder, or recent heart attack;
a personal or family history of mental illness, psychotic disorder, bipolar illness, depression, or suicide attempt;
epilepsy or other seizure disorder; or
tics (muscle twitches) or Tourette's syndrome.
Long-term use of lisdexamfetamine can slow a child's growth. Tell your doctor if the child using this medication is not growing or gaining weight properly.Do not give this medication to a child younger than 6 years old without the advice of a doctor. Lisdexamfetamine may be habit-forming and should be used only by the person it was prescribed for. Lisdexamfetamine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Using this medication improperly can cause death or serious side effects on the heart.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication. You may also be asked to not use the medication for a day or two and watch for any differences in behavior off the medication.Take this medication with a full glass of water.
It is best to take this medication in the morning. Do not take lisdexamfetamine in the afternoon or evening because it may cause sleep problems (insomnia).
You may take lisdexamfetamine with or without food.
The capsule should be swallowed whole. You may also open the lisdexamfetamine capsule and sprinkle the medicine into a glass of water. After the medicine has dissolved, drink this mixture right away. Do not save the mixture for later use. Discard the empty capsule.
To be sure this medication is helping your condition, your doctor will need to see you on a regular basis. Do not miss any scheduled appointments.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using lisdexamfetamine.Store lisdexamfetamine at room temperature away from moisture, heat, and light. Keep track of how many capsules have been used from each new bottle of this medicine. Lisdexamfetamine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.
See also: Lisdexamfetamine dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, or if it is already evening, skip the missed dose and take the medicine the next morning. Taking this medicine late in the day can cause sleep problems. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include restlessness, tremor, muscle twitches, rapid breathing, confusion, hallucinations, panic, aggressiveness, unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine. These symptoms may be followed by depression and tiredness. Other overdose symptoms include nausea, vomiting, diarrhea, stomach pain, uneven heartbeats, feeling light-headed, fainting, seizure (convulsions), or coma.
Avoid drinking fruit juices or taking vitamin C at the same time you take lisdexamfetamine. These can make your body absorb less of the medicine.
Stop using lisdexamfetamine and call your doctor at once if you have any of these serious side effects:
fast, pounding, or uneven heartbeats;
decreased blood pressure (feeling light-headed, fainting);
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
tremor, restlessness, hallucinations, unusual behavior, or motor tics (muscle twitches).
Less serious side effects may include:
nausea, vomiting, stomach pain, loss of appetite, weight loss;
sleep problems (insomnia); or
dry mouth or an unpleasant taste in your mouth.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Attention Deficit Disorder:
Initial dose: 30 mg orally once a day in the morningIf necessary, the initial daily dose may be increased by 10 mg to 20 mg approximately once a week up to a maximum daily dose of 70 mg
Usual Pediatric Dose for Attention Deficit Disorder:
6 to 12 years:Initial dose: 30 mg orally once a day in the morningIf necessary, the initial daily dose may be increased by 10 mg to 20 mg approximately once a week up to a maximum daily dose of 70 mg.Lisdexamfetamine has not been studied in children under 6 years of age or adolescents. Long-term effects of amphetamines in children have not been well established. Amphetamines are not recommended for use in children under 3 years of age.
Before taking lisdexamfetamine, tell your doctor if you are using any of the following drugs:
ammonium chloride, ascorbic acid (vitamin C), K-Phos;
blood pressure medications;
a diuretic (water pill);
cold or allergy medicines (antihistamines);
lithium (Eskalith, Lithobid);
methenamine (Hiprex, Mandelamine, Urex);
phenytoin (Dilantin), phenobarbital (Luminal, Solfoton);
pain medication such as meperidine (Demerol) or propoxyphene (Darvon, Darvocet); or
an antidepressant such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), or nortriptyline (Pamelor).
This list is not complete and there may be other drugs that can interact with lisdexamfetamine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.