Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index

Drugs A-Z List

Diseases & Conditions A-Z List

Herbs & Supplements

Medical Dictionary

Full Article

Popular Drugs

Popular Diseases & Conditions

Drugs reference index «Amitiza»



Generic name: LubiprostoneBrand names: Amitiza

Why is Amitiza prescribed?

Amitiza is used to relieve chronic constipation when the cause is unknown. It is intended to treat constipation that has lasted for 3 months or more and that is not due to an underlying illness or medication side effect.

Most important fact about Amitiza

Amitiza has not been studied in pregnant women and should only be used during pregnancy if the potential benefits justify the potential risk to the fetus. Women should have a negative pregnancy test before beginning treatment with Amitiza and need to use contraception to prevent pregnancy while being treated with the drug. If you are pregnant or become pregnant while taking Amitiza, talk with your doctor to evaluate the risks.

How should you take Amitiza?

Unless instructed otherwise by your doctor, take Amitiza twice a day, with food or a meal. Most people have a bowel movement within 24 hours of taking their first dose.

  • If you miss a dose...Take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
  • Storage instructions...Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Amitiza.

  • Side effects may include:Diarrhea, headache, nausea

Why should Amitiza not be prescribed?

Do not take Amitiza if you:

  • Have a history of bowel obstruction.
  • Are pregnant, unless, after discussion with your doctor, the potentialbenefit justifies the potential risk to the fetus.
  • Have severe diarrhea.
  • Are allergic to Amitiza or any of its ingredients.

Special warnings about Amitiza

Tell your doctor about your complete medical history, especially if you have ever been told you have a bowel obstruction or you have kidney or liver problems.

Let the doctor know if you cannot swallow capsules; you may not be able to take Amitiza.

Before beginning treatment with Amitiza, be sure to tell the doctor about all prescription, over-the-counter, and herbal medications you are taking.

Tell your doctor if you experience nausea while taking Amitiza; the doctor may be able to suggest ways to manage this side effect.

If you get diarrhea during treatment or your diarrhea worsens, stop taking Amitiza and contact your doctor immediately.

Amitiza has not been studied in children under 18 years old.

Possible food and drug interactions when taking Amitiza

Although studies have suggested a low risk of interactions with other drugs and products, only your doctor can decide whether Amitiza is right for you. It is important to check with your doctor before combining Amitiza with any other medication or dietary supplement.

Special information if you are pregnant or breastfeeding

The effects of Amitiza during pregnancy are unknown (see "Most important fact about Amitiza"). It is also not known whether Amitiza appears in breast milk. If you would like to breastfeed, discuss your options with your doctor

Recommended dosage for Amitiza


The recommended dosage is 24 micrograms taken twice a day with food.


There is little information on the potential results of Amitiza overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

  • Symptoms of Amitiza overdose may include:Abdominal pain, breathing problems, diarrhea, dizziness, feeling faint or lightheaded, headache, loose or watery stools, pale skin, severe nausea, skin flushing, vomiting
  • Amitiza Prescribing Information (FDA)
  • Amitiza Consumer Overview
  • Amitiza Advanced Consumer (Micromedex) - Includes Dosage Information
  • Amitiza MedFacts Consumer Leaflet (Wolters Kluwer)
  • Lubiprostone Professional Patient Advice (Wolters Kluwer)

Comment «Amitiza»