Generic Name: amlodipine and olmesartan (am LOE de peen ol me SAR tan)Brand Names: Azor
Amlodipine is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels.
Olmesartan is in a group of drugs called angiotensin II receptor antagonists. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
The combination of amlodipine and olmesartan is used to treat high blood pressure (hypertension).
Amlodipine and olmesartan may also be used for other purposes not listed in this medication guide.What is the most important information I should know about amlodipine and olmesartan?Do not use this medication without telling your doctor if you are pregnant. Olmesartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.Do not use potassium supplements or salt substitutes while you are taking amlodipine and olmesartan, unless your doctor has told you to. Call your doctor at once if you have swelling in your hands or feet, rapid weight gain, fast or pounding heartbeats, jaundice (yellowing of the skin or eyes), chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, or if you feel like you might pass out. In rare cases, amlodipine and olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.What should I discuss with my healthcare provider before taking amlodipine and olmesartan?You should not use this medication if you are allergic to amlodipine (Norvasc) or olmesartan (Benicar).
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take amlodipine and olmesartan.
congestive heart failure;
if you are vomiting or having diarrhea; or
if you have recently had a heart attack.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.Take this medication with a full glass (8 ounces) of water.
You may take this medication with or without food.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney function may also need to be tested. Do not miss any scheduled visits to your doctor.If you need to undergo kidney dialysis or have any type of surgery, tell the doctor ahead of time that you are using amlodipine and olmesartan.
Keep using this medication even if you feel fine. High blood pressure often has no symptoms.Store amlodipine and olmesartan at room temperature away from moisture and heat.
See also: Amlodipine and olmesartan dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include fast heart rate, warmth or tingling, feeling light-headed, or fainting.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.Do not use potassium supplements or salt substitutes while you are taking amlodipine and olmesartan, unless your doctor has told you to.
feeling like you might pass out;
swelling in your hands or feet, rapid weight gain;
fast or pounding heartbeats;
urinating less than usual or not at all;
jaundice (yellowing of the skin or eyes); or
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.
Less serious side effects include:
warmth, redness, or tingly feeling under your skin;
hair loss; or
mild skin rash or itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Hypertension:
Initial dose: 1 tablet orally once a day.The dosage of amlodipine-olmesartan should be based on the patient's requirements for each drug. The recommended dosage range for hypertension is 5 to 10 mg (amlodipine) and 20 to 40 mg (olmesartan) orally per day. Amlodipine-olmesartan may be used as initial therapy in patients who are likely to need multiple antihypertensive agents to achieve their blood pressure goals.
Before taking amlodipine and olmesartan, tell your doctor if you are using any of the following drugs:
potassium supplements or salt substitutes;
diuretics (water pills); or
other medications that lower blood pressure.
This list is not complete and there may be other drugs that can interact with amlodipine and olmesartan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.