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Drugs reference index «Amlodipine besylate»

Amlodipine besylate

Brand names: Norvasc

Why is Amlodipine besylate prescribed?

Norvasc is prescribed for angina, a condition characterized by episodes of crushing chest pain that usually results from a lack of oxygen in the heart muscle due to clogged arteries. Norvasc is also prescribed for high blood pressure. It is a type of medication called a calcium channel blocker. These drugs dilate blood vessels and slow the heart to reduce blood pressure and the pain of angina.

Most important fact about Amlodipine besylate

If you have high blood pressure, you must take Norvasc regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Norvasc; and you must continue taking it even if you are feeling well. Norvasc does not cure high blood pressure; it merely keeps it under control.

How should you take Amlodipine besylate?

Norvasc may be taken with or without food. A once-a-day medication, Norvasc may be used alone or in combination with other drugs for high blood pressure or angina.

You should take Amlodipine besylate exactly as prescribed, even if your symptoms have disappeared. You will begin to see a drop in your blood pressure 24 hours after you start the medication.

  • If you miss a dose...If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
  • Storage instructions...Store at room temperature in a tightly closed container, away from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Norvasc.

  • Side effects may include:Dizziness, fatigue, flushing, fluid retention and swelling, headache, palpitations (fluttery or throbbing heartbeat)

Why should Amlodipine besylate not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Norvasc, do not take Amlodipine besylate.

Special warnings about Amlodipine besylate

Check with your doctor before you stop taking Norvasc, as a slow reduction in the dose may be needed.

Your doctor will prescribe Norvasc with caution if you have certain heart conditions or liver disease. Make sure the doctor is aware of all your medical problems before you start therapy with Norvasc.

Although very rare, if you have severe heart disease, you may experience an increase in frequency and duration of angina attacks, or even have a heart attack, when you are starting on Norvasc or your dosage is increased.

Safety and effectiveness in children less than 6 years old have not been established.

Possible food and drug interactions when taking Amlodipine besylate

There are no known food or drug interactions with Amlodipine besylate.

Special information if you are pregnant or breastfeeding

The effects of Norvasc during pregnancy have not been adequately studied. If you are pregnant or planning to become pregnant, tell your doctor immediately. Norvasc should be used during pregnancy only if clearly needed. Norvasc may appear in breast milk. If Amlodipine besylate is essential to your health, your doctor may tell you to discontinue breastfeeding your baby until your treatment with Norvasc is finished.

Recommended dosage for Amlodipine besylate

HIGH BLOOD PRESSURE

Adults

The usual starting dose is 5 milligrams taken once a day. The most you should take in a day is 10 milligrams. If your doctor is adding Norvasc to other high blood pressure medications, the dose is 2.5 milligrams once daily. The lower 2.5-milligram starting dose also applies if you have liver disease.

Children 6 to 17 Years Old

The usual dose is 2.5 to 5 milligrams once a day. Doses exceeding 5 milligrams have not been studied in children.

Older Adults

You will be prescribed a lower starting dose of 2.5 milligrams.

ANGINA

Adults

The usual starting dose is 5 to 10 milligrams once daily. If you have liver disease, the lower 5-milligram dose will be used at the start.

Older Adults

The usual starting dose is 5 milligrams. Your doctor may adjust the dose based on your response to the drug.

Overdosage

Experience with Norvasc is limited; but if you suspect an overdose, seek medical attention immediately. The most likely symptoms are a drop in blood pressure and a faster heartbeat.

  • Amlodipine Prescribing Information (FDA)
  • Amlodipine Professional Patient Advice (Wolters Kluwer)
  • amlodipine Advanced Consumer (Micromedex) - Includes Dosage Information
  • Amlodipine MedFacts Consumer Leaflet (Wolters Kluwer)
  • Norvasc Prescribing Information (FDA)
  • Norvasc Consumer Overview

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