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Drugs reference index «acetaminophen and chlorpheniramine»

acetaminophen and chlorpheniramine

Generic Name: acetaminophen and chlorpheniramine (a SEET a MIN oh fen and KLOR fen IR a meen)Brand names: Coricidin, Coricidin HBP Cold & Flu

What is acetaminophen and chlorpheniramine?

Acetaminophen is a pain reliever and a fever reducer.

Chlorpheniramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Chlorpheniramine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

The combination of acetaminophen and chlorpheniramine is used to treat runny nose, sneezing, watery eyes, and pain or fever caused by allergies, the common cold, or the flu.

Acetaminophen and chlorpheniramine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about acetaminophen and chlorpheniramine?Do not take more of this medication than is recommended. An overdose of acetaminophen can cause damage to your liver. Do not use any other cough, cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains acetaminophen (sometimes abbreviated as "APAP") or chlorpheniramine. Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen, and can add to drowsiness caused by an antihistamine. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor's advice, and never take more than 2 grams (2000 mg) per day.What should I discuss with my healthcare provider before taking acetaminophen and chlorpheniramine?Do not take this medication if you are allergic to acetaminophen, chlorpheniramine, or any antihistamine.

Ask a doctor or pharmacist about using acetaminophen and chlorpheniramine if you have:

  • liver disease;

  • glaucoma;

  • kidney disease;

  • an enlarged prostate; or

  • problems with urination.

Do not take this medication without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains acetaminophen.

It is not known whether acetaminophen and chlorpheniramine will harm an unborn baby. Before taking this medication, tell your doctor if you are pregnant. It is not known whether acetaminophen and chlorpheniramine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take acetaminophen and chlorpheniramine?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

An overdose of acetaminophen can cause serious harm. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Taking more acetaminophen could cause damage to your liver. One Coricidin tablet contains 325 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking. If you drink more than three alcoholic beverages per day, do not take acetaminophen without your doctor's advice, and never take more than 2 grams (2000 mg) of acetaminophen per day. Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store acetaminophen and chlorpheniramine at room temperature away from moisture and heat.

See also: Acetaminophen and chlorpheniramine dosage in more detail

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include dizziness, drowsiness, feeling restless or nervous, dry mouth, warmth or tingly feeling, nausea, vomiting, diarrhea, stomach pain, loss of appetite, increased sweating, seizure (convulsions), or coma.

What should I avoid while taking acetaminophen and chlorpheniramine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not use any other cough, cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as "APAP") and chlorpheniramine are contained in many combination medicines. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains acetaminophen, APAP or chlorpheniramine. Avoid drinking alcohol. It can increase the risk of liver damage while you are taking acetaminophen, and can add to drowsiness caused by chlorpheniramine.

Acetaminophen and chlorpheniramine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
  • fast, pounding, or uneven heartbeats;

  • confusion, hallucinations, unusual thoughts or behavior;

  • severe dizziness, anxiety, restless feeling, or nervousness;

  • urinating less than usual or not at all;

  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • dryness of the eyes, nose, and mouth;

  • blurred vision;

  • difficulty urinating;

  • dizziness, drowsiness;

  • problems with memory or concentration;

  • ringing in your ears;

  • restless or excitability (especially in children); or

  • mild nausea, stomach pain, constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Acetaminophen and chlorpheniramine Dosing Information

Usual Adult Dose for Allergic Rhinitis:

2 tablets orally every 4 to 6 hoursMaximum dose: 12 in 24 hours or as directed by a doctor

Usual Adult Dose for Cold Symptoms:

2 tablets orally every 4 to 6 hoursMaximum dose: 12 in 24 hours or as directed by a doctor

Usual Adult Dose for Influenza:

2 tablets orally every 4 to 6 hoursMaximum dose: 12 in 24 hours or as directed by a doctor

Usual Adult Dose for Rhinorrhea:

2 tablets orally every 4 to 6 hoursMaximum dose: 12 in 24 hours or as directed by a doctor

Usual Pediatric Dose for Allergic Rhinitis:

>=12 years:2 tablets orally every 4 to 6 hoursMaximum dose: 12 tablets in 24 hours or as directed by a doctor6 to <12 years:1 tablets orally every 4 to 6 hoursMaximum dose: 5 tablets in 24 hours or as directed by a doctor

Usual Pediatric Dose for Cold Symptoms:

>=12 years:2 tablets orally every 4 to 6 hoursMaximum dose: 12 tablets in 24 hours or as directed by a doctor6 to <12 years:1 tablets orally every 4 to 6 hoursMaximum dose: 5 tablets in 24 hours or as directed by a doctor

Usual Pediatric Dose for Influenza:

>=12 years:2 tablets orally every 4 to 6 hoursMaximum dose: 12 tablets in 24 hours or as directed by a doctor6 to <12 years:1 tablets orally every 4 to 6 hoursMaximum dose: 5 tablets in 24 hours or as directed by a doctor

Usual Pediatric Dose for Rhinorrhea:

>=12 years:2 tablets orally every 4 to 6 hoursMaximum dose: 12 tablets in 24 hours or as directed by a doctor6 to <12 years:1 tablets orally every 4 to 6 hoursMaximum dose: 5 tablets in 24 hours or as directed by a doctor

What other drugs will affect acetaminophen and chlorpheniramine?

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by chlorpheniramine. Tell your doctor if you regularly use any of these other medicines.

Tell your doctor about all other medications you use, especially:

  • isoniazid;

  • zidovudine (Retrovir, AZT);

  • an antidepressant;

  • a diuretic (water pill);

  • probenecid (Benbemid);

  • medication to treat irritable bowel syndrome;

  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

  • aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others); or

  • seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).

This list is not complete and there may be other drugs that can interact with acetaminophen and chlorpheniramine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about acetaminophen and chlorpheniramine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.05. Revision Date: 07/28/2009 3:22:43 PM.

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