Generic Name: thiothixene (THYE oh THIX een)Brand Names: Navane
Thiothixene is an antipsychotic medication. It affects the actions of chemicals in your brain.
Thiothixene is used to treat schizophrenia.
Thiothixene may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Navane (thiothixene)?Thiothixene is not for use in psychotic conditions related to dementia. Thiothixene may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.You should not use this medication if you are allergic to thiothixene, or if you have a blood cell disorder such as anemia or low white blood cells or platelets, or if you have decreased alertness caused by taking certain medications or drinking alcohol.
Call your doctor at once if you have restless muscle movements in your eyes, tongue, jaw, or neck. Thiothixene can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid drinking alcohol. You should not take thiothixene if you are under the effects of alcohol.Avoid becoming overheated or dehydrated during exercise and in hot weather. Thiothixene can decrease perspiration and you may be more prone to heat stroke.
What should I discuss with my healthcare provider before taking Navane (thiothixene)?Thiothixene is not for use in psychotic conditions related to dementia. Thiothixene may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not use this medication if you are allergic to thiothixene, or if you have:a blood cell disorder such as anemia, low white blood cell counts, or low platelets; or
drowsiness, slow breathing, weak pulse, or decreased alertness caused by taking certain medications or drinking alcohol.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use thiothixene:
epilepsy or other seizure disorder;
heart disease;
a history of breast cancer; or
if you are addicted to alcohol.
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take thiothixene with a full glass of water.This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using thiothixene.
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
You may not start feeling better right away when you start taking thiothixene. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve during treatment. Store thiothixene at room temperature away from moisture and heat.Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include drowsiness, dizziness, muscle stiffness or twitching, increased salivation, trouble swallowing, weakness, loss of balance or coordination, and fainting.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid drinking alcohol. You should not take thiothixene if you are under the effects of alcohol.Avoid becoming overheated or dehydrated during exercise and in hot weather. Thiothixene can decrease perspiration and you may be more prone to heat stroke.
Avoid exposure to sunlight whenever possible.very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out;
restless muscle movements in your eyes, tongue, jaw, or neck;
tremor (uncontrolled shaking);
trouble swallowing;
vision changes;
swelling in your hands or feet;
seizure (convulsions);
pale skin, easy bruising or bleeding, unusual weakness; or
fever, chills, body aches, flu symptoms.
Less serious side effects may include:
dizziness or drowsiness;
feeling restless or agitated;
sleep problems (insomnia);
breast swelling or discharge;
changes in your menstrual periods;
nausea, vomiting, diarrhea, constipation;
changes in weight or appetite;
dry mouth, increased thirst; or
impotence, loss of interest in sex.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you use, especially:
carbamazepine (Tegretol);
blood pressure medications;
atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
glycopyrrolate (Robinul);
mepenzolate (Cantil);
bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).
This list is not complete and there may be other drugs that can interact with thiothixene. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.