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Drugs reference index «Neulasta»



Generic Name: Pegfilgrastim (peg-fil-GRAS-tim)Brand Name: Neulasta

Neulasta is used for:

Decreasing the incidence of infection in certain cancer patients undergoing myelosuppressive cancer treatments.

Neulasta is an amino acid. It works by stimulating bone marrow to produce white blood cells, which fight infection.

Do NOT use Neulasta if:

  • you are allergic to any ingredient in Neulasta , filgrastim, or Escherichia coli (E. coli)-derived proteins

Contact your doctor or health care provider right away if any of these apply to you.

Before using Neulasta :

Some medical conditions may interact with Neulasta . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have other blood problems (eg, sickle cell anemia), bone marrow leukemia, spleen problems, lung or breathing problems, or a blood or tissue infection
  • if you are or will be undergoing chemotherapy or radiation therapy

Some MEDICINES MAY INTERACT with Neulasta . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Lithium because it may increase the risk of Neulasta 's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Neulasta may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Neulasta :

Use Neulasta as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Neulasta . Talk to your pharmacist if you have questions about this information.
  • Neulasta is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Neulasta at home, a health care provider will teach you how to use it. Be sure you understand how to use Neulasta . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not shake Neulasta .
  • Do not use Neulasta if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Neulasta , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Neulasta .

Important safety information:

  • Serious and sometimes fatal spleen problems (including spleen rupture) have been reported in patients using Neulasta . Notify your doctor immediately if you experience left-sided upper stomach pain and/or shoulder tip pain.
  • Neulasta may reduce the chance of infection, but it does not prevent all infection. Tell your doctor right away if you notice symptoms of infection (eg, fever; chills; sore throat; diarrhea; redness, swelling, or pain around a cut or sore) while you take Neulasta .
  • Tell your doctor if you develop a lump, swelling, or bruising at the injection site that does not go away.
  • Tell your doctor or dentist that you take Neulasta before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including blood cell counts, may be performed while you use Neulasta . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Neulasta should not be used in INFANTS, CHILDREN, or SMALLER ADOLESCENTS weighing less than 100 pounds (45 kilograms); safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Neulasta while you are pregnant. It is not known if Neulasta is found in breast milk. If you are or will be breast-feeding while you use Neulasta , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Neulasta :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bone or joint pain; constipation; muscle pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; dizziness; fast heartbeat; increased sweating; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); fast breathing; fever; left-sided shoulder tip pain; left-sided upper stomach pain; a lump, swelling, or bruising at the injection site; severe or persistent bone, chest, joint, or stomach pain; shortness of breath; swelling of the hands, feet, arms, or legs; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Neulasta :

Store Neulasta in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C), in the original carton. Do not freeze. If accidentally frozen, allow the medicine to thaw in the refrigerator. If frozen more than once, the medicine should be thrown away. If Neulasta is left at room temperature for more than 48 hours, it should be discarded. Protect from light. Keep Neulasta , as well as needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about Neulasta , please talk with your doctor, pharmacist, or other health care provider.
  • Neulasta is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Neulasta . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Neulasta Prescribing Information (FDA)
  • Neulasta Advanced Consumer (Micromedex) - Includes Dosage Information
  • Neulasta Consumer Overview
  • Pegfilgrastim Professional Patient Advice (Wolters Kluwer)

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