Generic Name: methscopolamine (METH skoe POL a meen)Brand Names: Pamine, Pamine Forte
Methscopolamine reduces the secretions of certain organs in the body, such as the stomach.
Methscopolamine is used to reduce stomach acid secretion to help control peptic ulcers.
This medication does not help heal a stomach ulcer.
Methscopolamine may also be used for other purposes not listed in this medication guide.What is the most important information I should know about Pamine (methscopolamine)?You should not take this medication if you have glaucoma, urination problems due to a bladder obstruction, myasthenia gravis, a stomach disorder called paralytic ileus, or a blockage in your intestines, or severe ulcerative colitis with toxic megacolon.
Before taking methscopolamine, tell your doctor if you are allergic to any drugs, or if you have ulcerative colitis, kidney or liver disease, a thyroid disorder, high blood pressure or heart disease, a heart rhythm disorder, an enlarged prostate, or if you have had an ileostomy or colostomy.
To be sure this medication is helping your condition, you may need blood tests and x-rays or other scans of your stomach or intestines on a regular basis. Your stools may also need to be tested for the presence of blood. Do not miss any scheduled appointments.Methscopolamine can cause side effects that may impair your vision, thinking, or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by methscopolamine. Tell your doctor if you regularly use any of these medicines. Avoid drinking alcohol. It can increase some of the side effects of methscopolamine.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Methscopolamine can decrease perspiration and you may be more prone to heat stroke.Stop using this medication and call your doctor at once if you diarrhea, fast or pounding heartbeats, or if you are urinating less than usual or not at all. Older adults may be more sensitive to the side effects of methscopolamine.What should I discuss with my healthcare provider before taking Pamine (methscopolamine)?You should not take this medication if you are allergic to methscopolamine, or if you have:
if you are unable to urinate due to a bladder obstruction;
a stomach disorder called paralytic ileus; or
a blockage in your intestines, or severe ulcerative colitis with toxic megacolon.
Before taking methscopolamine, tell your doctor if you are allergic to any drugs, or if you have:
a thyroid disorder;
high blood pressure (hypertension);
heart disease, congestive heart failure;
a heart rhythm disorder;
an enlarged prostate and problems with urination; or
if you have had an ileostomy or colostomy.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use methscopolamine.FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether methscopolamine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more sensitive to the side effects of methscopolamine.
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.Methscopolamine is usually taken 30 minutes before meals and at bedtime.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
To be sure this medication is helping your condition, you may need blood tests and x-rays or other scans of your stomach or intestines on a regular basis. Your stools may also need to be tested for the presence of blood. Do not miss any scheduled appointments.Store methscopolamine at room temperature away from moisture and heat.
See also: Pamine dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include muscle weakness or limpness, feeling restless or excited, unusual thoughts or behavior, numbness, warmth or tingling under your skin, or feeling like you might pass out.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Methscopolamine can decrease perspiration and you may be more prone to heat stroke.
fast or pounding heartbeats;
urinating less than usual or not at all.
Less serious side effects may include:
sleep problems (insomnia);
blurred vision, increased sensitivity to light;
headache, dizziness, confusion;
dry mouth, decreased sense of taste;
nausea, vomiting, bloating, constipation;
impotence, loss of interest in sex, or trouble having an orgasm;
decreased sweating; or
mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Many drugs can interact with methscopolamine. Below is just a partial list. Tell your doctor if you are using:
digoxin (digitalis, Lanoxin);
an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), doxepin (Sinequan), imipramine (Janimine, Tofranil), and others;
medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), or trifluperazine (Stelazine);
atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).
This list is not complete and there may be other drugs that can interact with methscopolamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.