Skin problems, including acne-like rash, cracking, dryness, infection of the fingernails or toenails, itching, and redness, are common with Panitumumab . Severe skin problems, including swollen, blistered, or peeling skin; skin infection; and infected sores (abscesses) may also occur. Serious and sometimes fatal systemic infections have also occurred along with severe skin problems. Be sure to report any unusual skin changes to your doctor right away.
Some patients may experience a reaction when they receive Panitumumab . Symptoms may include chills, dizziness or lightheadedness, fever, trouble breathing, or unusual hoarseness. Tell your health care provider right away if you have any of these symptoms. Discuss the risks and benefits of using Panitumumab with your doctor.
Treating certain types of colon or rectal cancer that have spread to other parts of the body. It may also be used for other conditions as determined by your doctor.
Panitumumab is a monoclonal antibody. It works to treat certain types of cancer by binding to a protein (endothelial growth factor receptor [EGFR]) found on cancer cells. This reduces the growth and survival of the cancer.
Contact your doctor or health care provider right away if this applies to you.
Some medical conditions may interact with Panitumumab . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Panitumumab . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Panitumumab may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Panitumumab as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Panitumumab .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; eyelash growth; mild acne; mild dryness, itching, or redness of the skin; nausea; stomach pain; tiredness; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest congestion or tightness; chest pain; cough; increased tearing; irritation, pain, redness, or swelling of the eye or eyelid; irritation, redness, swelling, or sores in or around the mouth; moderate to severe skin changes (eg, blistered, cracking, peeling, swollen, or painful skin; moderate to severe acne; moderate to severe redness or itching); pain, redness, or swelling at the injection site; pain, redness, or swelling near the nailbed; severe or persistent diarrhea, nausea, or vomiting; shortness of breath; signs of infection (eg, chills, fever, sore throat); swelling of the ankles, feet, or hands; vision changes; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms of overdose may include persistent dry gums or eyes, diarrhea, fatigue, or lack of feeling alert.Proper storage of Panitumumab :
Panitumumab is usually handled and stored by a health care provider. If you are using Panitumumab at home, store Panitumumab as directed by your pharmacist or health care provider. Keep Panitumumab out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Panitumumab . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.