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Drugs reference index «pantoprazole»

pantoprazole (Oral route)

pan-TOE-pra-zole

Commonly used brand name(s):

In the U.S.

  • Protonix

Available Dosage Forms:

  • Tablet
  • Tablet, Enteric Coated
  • Packet

Pharmacologic Class: Proton Pump Inhibitor

Uses For pantoprazole

Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat erosive esophagitis or "heartburn" caused by gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus. pantoprazole may also be used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid .

Pantoprazole works by decreasing the amount of acid produced by the stomach .

pantoprazole is available only with your doctor's prescription .

Before Using pantoprazole

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pantoprazole, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to pantoprazole or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of pantoprazole in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of pantoprazole in the elderly .

Pregnancy

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using pantoprazole with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Atazanavir
  • Clopidogrel
  • Dasatinib
  • Erlotinib
  • Mycophenolate Mofetil
  • Nelfinavir

Using pantoprazole with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Cranberry
  • Itraconazole
  • Methotrexate
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of pantoprazole. Make sure you tell your doctor if you have any other medical problems, especially:

  • Vitamin B-12 deficiency—If used for a long time, pantoprazole may make this condition worse .

Proper Use of pantoprazole

Swallow the delayed-release tablet whole. Do not split, crush, or chew it. You may take the tablet with or without food .

The delayed-release oral suspension granules should only be mixed with applesauce or apple juice. Do not mix the granules with water, other liquids, or food. Do not chew or crush the granules. Take the mixture at least 30 minutes before a meal. If you have a nasogastric feeding tube, make sure the tube is not clogged before you put pantoprazole in the tube with apple juice .

Dosing

The dose of pantoprazole will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of pantoprazole. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (delayed-release tablets or suspension):
    • For erosive esophagitis:
      • Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.
      • Children—Use and dose must be determined by your doctor .
    • For Zollinger-Ellison syndrome:
      • Adults—At first, 40 milligrams (mg) two times a day. Your doctor may increase your dose if needed.
      • Children—Use and dose must be determined by your doctor .

Missed Dose

If you miss a dose of pantoprazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using pantoprazole

It is very important that your doctor check your progress at regular visits to make sure pantoprazole is working properly and to check for unwanted effects .

Before you have any medical tests, tell the medical doctor in charge that you are taking pantoprazole. The results of some tests may be affected by pantoprazole .

Taking pantoprazole for a long time may make it harder for your body to absorb vitamin B-12. Tell your doctor if you have concerns about vitamin B-12 deficiency .

pantoprazole Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common
  • Abdominal pain
  • blurred vision
  • dry mouth
  • fatigue
  • flushed, dry skin
  • fruit-like breath odor
  • increased hunger
  • increased thirst
  • increased urination
  • nausea
  • sweating
  • troubled breathing
  • unexplained weight loss
  • vomiting
Incidence not known
  • Absence of or decrease in body movements
  • blindness
  • blistering, peeling, or loosening of skin
  • bloating
  • bloody or cloudy urine
  • bloody, black, or tarry stools
  • blurred vision
  • chills
  • clay-colored stools
  • constipation
  • continuous ringing or buzzing or other unexplained noise in ears
  • cough
  • dark-colored urine
  • decreased vision
  • diarrhea
  • difficulty with speaking
  • difficulty with swallowing
  • dizziness or lightheadedness
  • fast heartbeat
  • feeling of constant movement of self or surroundings
  • fever
  • general feeling of tiredness or weakness
  • greatly decreased frequency of urination or amount of urine
  • headache
  • hearing loss
  • high fever
  • hives
  • indigestion
  • itching
  • joint pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • loss of appetite
  • mood or mental changes
  • muscle cramps or spasms
  • muscle pain or stiffness
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pale skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • sensation of spinning
  • shortness of breath
  • skin rash
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach pain, continuing
  • swelling of the feet or lower legs
  • swollen glands
  • tightness in the chest
  • unexplained bleeding or bruising
  • unpleasant breath odor
  • unusual tiredness or weakness
  • vomiting of blood
  • wheezing
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Belching
  • bloated, full feeling
  • excess air or gas in the stomach or intestines
  • passing gas
  • sleeplessness
  • trouble sleeping
  • unable to sleep
Incidence not known
  • Increased watering of the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

  • Pantoprazole Prescribing Information (FDA)
  • Pantoprazole MedFacts Consumer Leaflet (Wolters Kluwer)
  • Protonix Prescribing Information (FDA)
  • Protonix Delayed-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)
  • Protonix Consumer Overview
  • Protonix Detailed Consumer Information (PDR)

See Also...

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