Generic Name: papaverine (pa PAV uh reen)Brand Names: Papacon, Para-Time S. R., Pavabid Plateau, Pavacot, Pavagen
Papaverine is in a class of drugs called vasodilators. Papaverine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. These actions may help to increase the amount of oxygen-rich blood in your brain, heart, and muscles.
Papaverine may also be useful in treating conditions involving spasms of the intestines and urinary tract.
Papaverine may also be used for purposes other than those listed in this medication guide.What is the most important information I should know about Pavagen (papaverine)?Use caution when driving, operating machinery, or performing other hazardous activities. Papaverine may cause dizziness. If you experience dizziness, avoid these activities. If you experience dizziness, rise slowly from a sitting or lying position to avoid falling. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking papaverine.
Notify your doctor if you experience especially bothersome sweating, rash, flushing, headache, tiredness, yellowing of your skin, nausea, decreased appetite, diarrhea, or constipation.
Before taking this medication, tell your doctor if you have
heart disease or irregular heartbeats,
You may not be able to take papaverine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.Papaverine is in the FDA pregnancy category C. This means that it is not known whether papaverine will harm an unborn baby. Do not take papaverine without first talking to your doctor if you are pregnant. It is not known whether papaverine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
Take papaverine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.Take each dose with a full glass of water. The regular-release form of papaverine is usually taken three to five times a day. The timed-release tablets and capsules are usually taken two or three times a day (every 8 to 12 hours). Follow your doctor's instructions. Do not crush, chew, break, or open the timed-release tablets or capsules. Swallow them whole. They are specially formulated to release slowly in your body. Store papaverine at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.
Symptoms of a papaverine overdose include drowsiness, weakness, double vision, poor coordination, headache, blue-colored lips or skin, and coma.
Stop taking papaverine and contact your doctor if your skin or eyes develop a yellow tint.
Other, less serious side effects may be more likely to occur. Continue to take papaverine and talk to your doctor if you experience
nausea, decreased appetite, diarrhea, or constipation;
dizziness or drowsiness;
sweating and flushing;
a rash; or
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Papaverine may decrease the effects of levodopa (Dopar, Larodopa) which is used to treat Parkinson's disease. You may need a change in your levodopa dosage if you are taking levodopa.
Drugs other than those listed here may also interact with papaverine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.