Generic Name: acetaminophen, caffeine, and dihydrocodeine (a SEET a MIN oh fen, KAF een, dye HYE droe KOE deen)Brand Names: Panlor DC, Panlor SS, Trezix, Zerlor
Dihydrocodeine is in a group of drugs called narcotic pain relievers.
Acetaminophen is a less potent pain reliever that increases the effects of dihydrocodeine.
Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
The combination of acetaminophen, caffeine, and dihydrocodeine is used to relieve moderate to severe pain.
Acetaminophen, caffeine, and dihydrocodeine may also be used for purposes other than those listed in this medication guide.What is the most important information I should know about acetaminophen, caffeine, and dihydrocodeine?
Tell your doctor if you drink more than three alcoholic beverages per day or if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains acetaminophen.Dihydrocodeine may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Tell your doctor if the medicine seems to stop working as well in relieving your pain.What should I discuss with my healthcare provider before taking acetaminophen, caffeine, and dihydrocodeine?Do not use this medication if you are allergic to acetaminophen (Tylenol) or dihydrocodeine, or if you have a stomach condition called paralytic ileus, or severe or uncontrolled asthma. Dihydrocodeine may be habit-forming and should be used only by the person it was prescribed for. This medicine should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medicine in a secure place where others cannot get to it.
Before using acetaminophen, caffeine, and dihydrocodeine, tell your doctor if you are allergic to any drugs, or if you have:
sleep apnea or other breathing disorders;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
low blood pressure;
a stomach or intestinal disorder;
a pancreas disorder;
Addison's disease or other adrenal gland disorder;
enlarged prostate, urination problems;
curvature of the spine;
mental illness; or
a history of drug or alcohol addiction.
If you have any of these conditions, you may not be able to use this medication, or you may need a dosage adjustment or special tests during treatment.
Tell your doctor if you drink more than three alcoholic beverages per day or if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains acetaminophen.FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby, but it could cause breathing problems or addiction/withdrawal symptoms in a newborn. Before you take acetaminophen, caffeine, and dihydrocodeine, tell your doctor if you are pregnant or plan to become pregnant during treatment. Dihydrocodeine can pass into breast milk and may harm a nursing baby. The use of this medication by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Older adults may be more sensitive to the effects of this medicine.
Take this medication exactly as it was prescribed for you. Do not take it in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.An overdose of acetaminophen can cause serious harm to your liver. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. Know the amount of acetaminophen in the specific product you are taking. You may have withdrawal symptoms when you stop using acetaminophen, caffeine, and dihydrocodeine after using it over a long period of time. Do not stop using this medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.
This medication can cause you to have unusual results with certain urine tests. Tell any doctor who treats you that you are using acetaminophen, caffeine, and dihydrocodeine.
If you need to have any type of surgery, tell the surgeon ahead of time that you are using acetaminophen, caffeine, and dihydrocodeine. You may need to stop using the medicine for a short time.Store the medicine at room temperature away from moisture and heat.
Keep track of how many tablets have been used from each new bottle of this medicine. Dihydrocodeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.
See also: Acetaminophen, caffeine, and dihydrocodeine dosage in more detail
Since this medication is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.
Overdose symptoms may include extreme drowsiness or insomnia, restless feeling, tremors, fast heart rate, sweating, pinpoint pupils, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), confusion, fainting, weak pulse, seizure (convulsions), coma, blue lips, shallow breathing, or no breathing.
While you are taking this medication, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice.
shallow breathing, slow heartbeat;
fast or pounding heart rate, feeling light-headed, fainting;
confusion, hallucinations, unusual thoughts or behavior;
problems with urination;
easy bruising or bleeding; or
nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects include:
feeling dizzy or drowsy, shaky or agitated;
mild nausea, vomiting, upset stomach; constipation, diarrhea;
mood changes, sleep problems (insomnia);
sweating, urinating more than usual;
ringing in your ears, blurred vision; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Pain:
Initial dosage: Panlor SS 1 tablet orally every 4 hours (not to exceed 1 tablet in a 4-hour period) or Panlor DC 2 capsules orally every 4 hoursMaximum daily dosage: Panlor SS 5 tablets in a 24-hour period; Panlor DC 10 capsules in a 24 hour period
Also tell your doctor if you use any of the following drugs:
atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), glycopyrrolate (Robinul), isoniazid, mepenzolate (Cantil), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
a blood thinner such as warfarin (Coumadin);
a bronchodilator such as ipratropium (Atrovent) or tiotropium (Spiriva);
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Levsin, and others), or propantheline (Pro-Banthine);
seizure medicine such as carbamazepine (Tegretol) or phenytoin (Dilantin); or
an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).
This is not a complete list and there may be other drugs that can interact with acetaminophen, caffeine, and dihydrocodeine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.