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Drugs reference index «Quinine»


Generic Name: Quinine (KWYE-nine)Brand Name: Qualaquin

Quinine is used for:

Treating malaria. It is usually used with other antimalarial medicines. It may also be used for other conditions as determined by your doctor.

Quinine is an antimalarial. It works by killing the malaria parasite.

Do NOT use Quinine if:

  • you are allergic to any ingredient in Quinine , or to mefloquine or quinidine
  • you have a history of a low platelet count (thrombocytopenia) or bleeding problems caused by using Quinine in the past
  • you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, ringing in the ears, inflammation of the optic (eye) nerve, myasthenia gravis, or a history of certain blood problems (eg, blackwater fever, intravascular hemolysis)
  • you have a certain type of irregular heartbeat (eg, QT prolongation)
  • you are taking astemizole, atorvastatin, a class IA antiarrhythmic (eg, disopyramide, procainamide, quinidine), a class III antiarrhythmic (eg, amiodarone, dofetilide, sotalol), cisapride, halofantrine, a macrolide antibiotic (eg, erythromycin, troleandomycin), pimozide, rifampin, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Quinine :

Some medical conditions may interact with Quinine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, irregular heartbeat), liver or kidney problems, depression, low blood sugar, seizures, or a family history of G6PD deficiency
  • if you have vision problems, eye pain, or a bleeding disorder (eg, thrombocytopenic purpura)
  • if you are scheduled for surgery or anesthesia

Some MEDICINES MAY INTERACT with Quinine . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Astemizole, class IA antiarrhythmics (eg, disopyramide, procainamide, quinidine), class III antiarrhythmics (eg, amiodarone, dofetilide, sotalol), cisapride, halofantrine, macrolide antibiotics (eg, erythromycin, troleandomycin), mefloquine, pimozide, or terfenadine because the risk of their side effects, including irregular heartbeat, may be increased by Quinine
  • Anticoagulants (eg, warfarin) because the risk of their side effects, such as bleeding, may be increased by Quinine
  • Atorvastatin because the risk of serious muscle problems (eg, muscle weakness) may be increased
  • Azole antifungals (eg, ketoconazole), H2 antagonists (eg, cimetidine), mefloquine, tetracycline antibiotics (eg, doxycycline), or urinary alkalizers (eg, acetazolamide, sodium bicarbonate) because they may increase the risk of Quinine 's side effects
  • Rifampin because it may decrease Quinine 's effectiveness
  • Carbamazepine, desipramine, digoxin, phenobarbital, or phenytoin because the risk of their side effects may be increased by Quinine
  • Anticholinesterase medicines (eg, neostigmine) or theophyllines (eg, aminophylline) because their effectiveness may be decreased by Quinine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Quinine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Quinine :

Use Quinine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Quinine . Talk to your pharmacist if you have questions about this information.
  • Take Quinine by mouth with food to reduce the risk of stomach upset.
  • Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Quinine .
  • Continue to take Quinine even if you feel well. Do not miss any doses.
  • If you miss a dose of Quinine , take it as soon as possible. If it has been more than 4 hours since the missed dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Quinine .

Important safety information:

  • Quinine may cause dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Quinine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If your symptoms do not get better within a few days or if they get worse, check with your doctor.
  • Tell your doctor or dentist that you take Quinine before you receive any medical or dental care, emergency care, or surgery.
  • Quinine may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Quinine . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Quinine may cause low blood sugar levels in some patients. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Use Quinine with caution in the ELDERLY; they may be more sensitive to its effects.
  • Quinine should be used with extreme caution in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Quinine while you are pregnant. Quinine is found in breast milk. If you are or will be breast-feeding while you use Quinine , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Quinine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; nausea; nervousness; restlessness; stomach cramps; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision, double vision, light sensitivity, blindness, or other unusual vision changes; chest pain; confusion; dark urine; decreased amount of urine or trouble urinating; decreased hearing, hearing loss, or ringing in the ears; fainting; fast or irregular heartbeat; fatigue; fever, chills, or sore throat; flushing; loss of appetite; mood or mental problems; personality changes; red, swollen, blistered, or peeling skin; seizures; severe dizziness or lightheadedness; severe or persistent stomach pain, nausea, vomiting, or diarrhea; sudden onset of cold sweat; unusual bleeding or bruising; unusual tiredness or weakness; weight loss; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include confusion; dilated pupils; loss of consciousness; nausea and vomiting; rash; ringing in the ears; seizures; severe dizziness; slow or irregular heartbeat; stomach cramping or pain; urine discoloration; vision loss.

Proper storage of Quinine :

Store Quinine at room temperature, between 77 and 86 degrees F (25 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Quinine out of the reach of children and away from pets.

General information:

  • If you have any questions about Quinine , please talk with your doctor, pharmacist, or other health care provider.
  • Quinine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Quinine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Quinine Natural MedFacts for Professionals (Wolters Kluwer)
  • quinine Concise Consumer Information (Cerner Multum)
  • quinine Advanced Consumer (Micromedex) - Includes Dosage Information
  • Qualaquin Prescribing Information (FDA)

See Also...

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