Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index
Search
EN

Drugs reference index «Reclast»

Reclast

Generic Name: zoledronic acid (Intravenous route)

zoe-le-DRON-ik AS-id

Commonly used brand name(s):

In the U.S.

  • Reclast
  • Zometa

Available Dosage Forms:

  • Solution
  • Powder for Solution

Therapeutic Class: Calcium Regulator

Chemical Class: Bisphosphonate

Uses For Reclast

Zoledronic acid is used to treat hypercalcemia (high levels of calcium in the blood) that may occur in patients with some types of cancer. It is also used to treat a cancer called multiple myeloma (tumors formed by the cells of the bone marrow) or certain types of bone metastases (the spread of cancer to the bone).

Zoledronic acid is used to treat Paget's disease of the bone in men and women. It is also used in men with osteoporosis and in women with osteoporosis who have gone through menopause. This medicine is used to reduce the risk of having more fractures in patients who have had a recent hip fracture.

This medicine is to be administered only by or under the supervision of your doctor.

This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, zoledronic acid is used in certain patients with the following medical conditions:

  • Bone loss, in men, from taking certain medicines for prostate cancer.
  • Bone loss, in breast cancer patients, from hormone therapy (prevention).

Before Using Reclast

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of zoledronic acid in children. However, safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of zoledronic acid in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution in patients receiving zoledronic acid.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersDStudies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Anemia or
  • Cancer, history of or
  • Cancer treatment, history of or
  • Dental disease, history of or
  • Poor dental hygiene, history of or
  • Radiation therapy, history of or
  • Steroid therapy, history of—May increase the risk for a serious jaw problem.
  • Asthma or
  • Heart disease or
  • Kidney disease—May make these conditions worse.
  • Bowel resection or
  • Parathyroid disease (e.g., hypoparathyroidism) or
  • Parathyroid surgery or
  • Stomach absorption problems or
  • Thyroid surgery—These conditions may increase your risk of having hypocalcemia (low levels of calcium in the blood).
  • Dehydration (not enough water or fluid in your body)—May increase the risk of severe kidney problems.
  • Hypocalcemia (low calcium in the blood) or
  • Kidney disease, severe—Should not be used in patients with these conditions.

Proper Use of zoledronic acid

This section provides information on the proper use of a number of products that contain zoledronic acid. It may not be specific to Reclast. Please read with care.

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed into one of your veins. The medicine must be injected slowly, so your IV tube will need to stay in place for at least 15 minutes.

Your doctor may also give you vitamins containing Vitamin D and calcium. Tell your doctor if you are unable to take these supplements.

Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems.

Precautions While Using Reclast

It is important that your doctor check your progress at regular visits after you have received zoledronic acid. If your condition has improved, your progress must still be checked. The results of laboratory tests or the occurrence of certain symptoms will tell your doctor if your condition is coming back and if a second treatment is needed. You will need a yearly dose of this medicine if you are being treated for postmenopausal osteoporosis, so check with your doctor regularly.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away. Do not breastfeed while you are using this medicine.

This medicine may cause low calcium in your blood. Check with your doctor immediately if you experience numbness or tingling around the mouth, or if you have muscle spasms.

Tell your doctor right away if you experience symptoms of agitation; blood in the urine; coma; confusion; decreased urine output; depression; dizziness; headache; irritability; lethargy; muscle twitching; nausea; rapid weight gain; seizures; stupor; swelling of the face, ankles, or hands; or unusual tiredness or weakness. These could be a sign of serious kidney problems.

It is important that you check with your doctor before having any dental procedures or surgeries done while you are receiving zoledronic acid. Tell your doctor right away if you experience jaw tightness, swelling, numbing, or pain or a loose tooth. It could be the sign of a serious jaw disease.

Tell your doctor if you have severe muscle, bone, or joint pain after receiving this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription (e.g., other medicines that also contain zoledronic acid) or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Reclast Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Agitation
  • black, tarry stools
  • blurred vision
  • chest pain
  • chills
  • coma
  • confusion
  • convulsions
  • cough
  • depression
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • fever
  • irregular heartbeat
  • irritability
  • lack or loss of strength
  • lethargy
  • lower back or side pain
  • mood or mental changes
  • muscle pain or cramps
  • muscle trembling or twitching
  • nausea or vomiting
  • numbness and tingling around the mouth, fingertips, or feet
  • painful or difficult urination
  • pale skin
  • rapid weight gain
  • seizures
  • shaking of the hands, arms, feet, legs, or face
  • shortness of breath, difficult or labored breathing
  • skin rash, cracks in the skin at the corners of the mouth, or soreness or redness around the fingernails and toenails
  • sore throat
  • sores, ulcers, or white spots on the lips or mouth
  • stupor
  • sudden sweating
  • swollen glands
  • tightness in the chest
  • trouble breathing with exercise
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • wheezing
Less common
  • Feeling of constant movement of self or surroundings
  • muscle cramps in the hands, arms, feet, legs, or face
  • muscle spasms
  • neck pain
  • pounding in the ears
  • rapid breathing
  • sensation of spinning
  • slow or fast heartbeat
  • sunken eyes
  • tingling of the hands or feet
  • tremor
Incidence not known
  • Decreased frequency or amount of urine
  • heavy jaw feeling
  • increased blood pressure
  • increased thirst
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loosening of a tooth
  • pain, swelling, or numbness in the mouth or jaw
  • swelling of the face, hands, fingers, lower legs, or ankles
  • troubled breathing
  • weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal pain
  • anxiety, nervousness, restlessness, or irritability
  • back pain
  • bad, unusual, or unpleasant (after) taste
  • bladder pain, bloody or cloudy urine
  • blistering, crusting, irritation, itching, or reddening of the skin
  • bone pain
  • burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  • change in taste
  • constipation
  • cracked lips
  • cracked, dry, or scaly skin
  • diarrhea
  • difficulty swallowing
  • discouragement
  • dry mouth
  • ear congestion
  • fear or nervousness
  • feeling sad or empty
  • frequent urge to urinate
  • hair loss or thinning hair
  • headache
  • hyperventilation
  • irregular heartbeats
  • joint pain or swollen joints
  • loss of appetite
  • loss of interest or pleasure
  • loss of voice
  • muscle stiffness or difficulty in moving
  • nasal congestion or runny nose
  • pain, swelling, or redness in the joints
  • partial loss of feeling
  • seeing, hearing, or feeling things that are not there
  • sleepiness or unusual drowsiness
  • sleeplessness, trouble sleeping, or unable to sleep
  • swelling or inflammation of the mouth
  • thirst
  • trouble with concentrating
  • unusually cold, shivering
  • vomiting
  • weight loss
Less common
  • Acid or sour stomach
  • belching
  • eye pain
  • heartburn
  • indigestion
  • stomach discomfort, upset, or pain
  • unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness
  • wrinkled skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

  • Reclast Prescribing Information (FDA)
  • Reclast MedFacts Consumer Leaflet (Wolters Kluwer)
  • Reclast Consumer Overview
  • Zoledronic Acid Professional Patient Advice (Wolters Kluwer)
  • Zoledronic Acid MedFacts Consumer Leaflet (Wolters Kluwer)
  • Aclasta Consumer Overview
  • Zometa Prescribing Information (FDA)
  • Zometa Consumer Overview

Comment «Reclast»