Aprotinin may cause severe and sometimes fatal allergic reactions (eg, rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; fast heartbeat; pale skin; severe low blood pressure; loss of consciousness possibly leading to a lack of heartbeat or breathing). The risk is increased in patients who have previously received Aprotinin . The risk of fatal allergic reactions may be greater in patients who receive Aprotinin more than once in a 12-month period of time. Tell your doctor if you think you have ever had Aprotinin in the past.
Reducing blood loss and the need for blood transfusions in patients undergoing certain types of heart surgery.
Aprotinin is a protease inhibitor. It works by reducing the inflammatory response associated with cardiopulmonary bypass surgery.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Aprotinin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Aprotinin . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Aprotinin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Aprotinin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Aprotinin .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; difficulty urinating; infection (eg, fever, chills, sore throat); lightheadedness; sleeplessness; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); asthma; chest pain; confusion; decreased urination; fast or irregular heartbeat; lung disorder; nausea; numbness of an arm or leg; one-sided weakness; severe stomach pain; sudden severe headache, dizziness, fainting, or vomiting; sudden weight gain; swelling of the hands, legs, or feet; vision or speech changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800 -222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Aprotinin :
Aprotinin is usually handled and stored by a health care provider. Keep Aprotinin out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Aprotinin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.