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Drugs reference index «Retrovir Syrup»

Retrovir Syrup


Retrovir Syrup

Generic Name: Zidovudine (zye-DOE-vyoo-deen)Brand Name: Retrovir

Severe blood problems have occurred in patients with HIV who are taking Retrovir Syrup. These problems include low white blood cell levels and severe anemia. Muscle pain or aches have occurred with long-term use of Retrovir Syrup.

High levels of lactic acid in the blood and severe liver problems have occurred in patients taking this type of medicine. These events have sometimes caused death.

Contact your doctor right away if dark urine, yellowing of the eyes or skin, stomach pain, unusual tiredness, muscle aches, fast breathing, drowsiness, fever, chills, or sore throat occurs.

Retrovir Syrup is used for:

Treating HIV infection when used along with other medicines. It is also used with other medicines to help prevent women from passing the HIV virus to the fetus during pregnancy.

Retrovir Syrup is an antiviral. It works by blocking the reproduction of the HIV virus.

Do NOT use Retrovir Syrup if:

  • you are allergic to any ingredient in Retrovir Syrup
  • you have an enlarged liver, high lactic acid levels in the blood, or abnormal liver function tests
  • you are taking doxorubicin, ribavirin, stavudine, or any medicine that contains zidovudine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Retrovir Syrup:

Some medical conditions may interact with Retrovir Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have bone marrow problems, low white blood cell levels, or liver or kidney problems
  • if you are very overweight

Some MEDICINES MAY INTERACT with Retrovir Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Zalcitabine because severe pancreas problems may occur
  • Fluconazole, ganciclovir, interferon alfa, probenecid, valproic acid, or any medicine that contains zidovudine because they may increase the risk of Retrovir Syrup's side effects
  • Doxorubicin, ribavirin, or stavudine because they may decrease Retrovir Syrup's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Retrovir Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Retrovir Syrup:

Use Retrovir Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Retrovir Syrup may be taken with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Use Retrovir Syrup on a regular schedule around the clock, unless otherwise directed by your doctor.
  • Continue to take Retrovir Syrup even if you feel well. Do not miss any doses.
  • It is important not to miss doses of Retrovir Syrup. If you miss a dose of Retrovir Syrup, take it as soon as your remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Retrovir Syrup.

Important safety information:

  • Retrovir Syrup may lower your body's ability to fight infection. Avoid contact with people who have colds or other infections. Contact your doctor if any signs of infection occur, such as fever, sore throat, rash, or chills.
  • Do not take more of Retrovir Syrup than directed without checking with your doctor. Do not take Retrovir Syrup for longer than directed without checking with your doctor.
  • Retrovir Syrup is not a cure for HIV infection. You may also still have infections or other illnesses that occur along with HIV. Remain under the care of your doctor.
  • Retrovir Syrup does not prevent you from giving HIV to other people through contact with blood or through sex. Use a barrier form of birth control (eg, condoms) if you have HIV. Do not share needles, other injection supplies, or personal items (eg, toothbrush, razor).
  • Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Retrovir Syrup. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.
  • Lab tests, including liver function, kidney function, and complete blood count, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANT WOMEN: Retrovir Syrup may not always prevent you from passing the HIV virus to the fetus. It is unknown how Retrovir Syrup may affect the baby later in life. Discuss any questions or concerns with your doctor.
  • PREGNANCY AND BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Retrovir Syrup during pregnancy. Retrovir Syrup is excreted in breast milk. Do not breast-feed while taking Retrovir Syrup. HIV-infected mothers should not breast-feed their infants because of the risk of transmitting the HIV infection or Retrovir Syrup.

Possible side effects of Retrovir Syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; loss of appetite; nausea; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills; dark urine; drowsiness; fast breathing; fever; muscle pain or aches; red, swollen, or blistered skin; seizures; shortness of breath; sore throat; stomach pain; unusual tiredness or weakness; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include severe or persistent headache; tiredness; vomiting.

Proper storage of Retrovir Syrup:

Store Retrovir Syrup at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Retrovir Syrup out of the reach of children and away from pets.

General information:

  • If you have any questions about Retrovir Syrup, please talk with your doctor, pharmacist, or other health care provider.
  • Retrovir Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Retrovir Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Retrovir Prescribing Information (FDA)
  • Retrovir Advanced Consumer (Micromedex) - Includes Dosage Information
  • Retrovir Detailed Consumer Information (PDR)
  • Retrovir Concise Consumer Information (Cerner Multum)
  • Zidovudine Prescribing Information (FDA)

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