Commonly used brand name(s):
In the U.S.
Available Dosage Forms:
Therapeutic Class: Central Nervous System Agent
Pharmacologic Class: Cholinesterase Inhibitor, Centrally Acting
Rivastigmineis used to treat the symptoms of mild to moderate Alzheimer's disease. Rivastigmine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. However, rivastigmine can improve thinking ability in some patients with Alzheimer's disease.
In Alzheimer's disease, many chemical changes take place in the brain. One of the earliest and biggest changes is that there is less of a chemical called acetylcholine (ACh). ACh helps the brain to work properly. Rivastigmine slows the breakdown of ACh, so it can build up and have a greater effect. However, as Alzheimer's disease gets worse, there will be less and less ACh, so rivastigmine may not work as well.
rivastigmine is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rivastigmine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to rivastigmine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Studies on rivastigmine have been done only in adult patients, and there is no specific information comparing use of rivastigmine in children with use in other age groups.
Studies on rivastigmine have been done only in middle-aged and older patients. Information on the effects of rivastigmine is based on these patients.
|All Trimesters||B||Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Using rivastigmine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of rivastigmine. Make sure you tell your doctor if you have any other medical problems, especially:
Take rivastigmine only as directed by your doctor.Do not take more or less of it, and do not take it more or less often than your doctor ordered. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.
Rivastigmine is best taken with food.
Rivastigmine seems to work best when it is taken at regularly spaced times, usually two times a day, in the morning and evening.
The dose of rivastigmine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of rivastigmine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of rivastigmine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
It is very important that your doctor check your progress at regular visits.
Tell your doctor if your symptoms get worse, or if you notice any new symptoms.
Before you have any kind of surgery, dental treatment, or emergency treatment, tell the doctor medical doctor or dentist in charge that you are taking rivastigmine. Taking rivastigmine together with medicines that are sometimes used during surgery or dental or emergency treatments may increase the effects of these medicines.
Rivastigmine may cause some people to become dizzy, clumsy, or unsteady. Make sure you know how you react to rivastigmine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.
Rivastigmine causes a large number of patients to have problems with their stomachs and intestines. Tell your doctor about any nausea, vomiting, stomach pain or loss of appetite.
Do not stop taking rivastigmine or decrease your dose without first checking with your doctor. Stopping rivastigmine suddenly or decreasing the dose by a large amount may cause mental or behavior changes.
If you think you or someone else may have taken an overdose of rivastigmine, get emergency help at once. Taking an overdose of rivastigmine may lead to convulsions (seizures) or shock. Some signs of shock are large pupils, irregular breathing, and fast weak pulse. Other signs of an overdose are severe nausea and vomiting, increasing muscle weakness, greatly increased sweating, and greatly increased watering of the mouth.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:More common
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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