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Drugs reference index «rizatriptan»

rizatriptan
rizatriptan


rizatriptan (Oral route)

rye-za-TRIP-tan

Commonly used brand name(s):

In the U.S.

  • Maxalt
  • Maxalt-MLT

Available Dosage Forms:

  • Tablet, Disintegrating
  • Tablet

Therapeutic Class: Antimigraine

Pharmacologic Class: Serotonin Receptor Agonist, 5-HT1

Uses For rizatriptan

Rizatriptan is used to treat severe migraine headaches. Many people find that their headaches go away completely after they take rizatriptan. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone.

Rizatriptan is not an ordinary pain reliever. It should not be used to relieve any kind of pain other than migraine headaches.

Rizatriptan may cause serious side effects in some people, especially people who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using rizatriptan as well as the good that it can do.

rizatriptan is available only with your doctor's prescription.

Before Using rizatriptan

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rizatriptan, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to rizatriptan or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing use of rizatriptan in children with use in other age groups.

Geriatric

Rizatriptan has been tested in elderly patients and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using rizatriptan with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Almotriptan
  • Dihydroergotamine
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Frovatriptan
  • Isocarboxazid
  • Linezolid
  • Methylergonovine
  • Methysergide
  • Naratriptan
  • Phenelzine
  • Procarbazine
  • Sumatriptan
  • Tranylcypromine
  • Zolmitriptan

Using rizatriptan with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Citalopram
  • Clovoxamine
  • Desvenlafaxine
  • Duloxetine
  • Escitalopram
  • Femoxetine
  • Fluoxetine
  • Fluvoxamine
  • Milnacipran
  • Nefazodone
  • Paroxetine
  • Reboxetine
  • Sertraline
  • Sibutramine
  • St John's Wort
  • Tapentadol
  • Venlafaxine
  • Zimeldine

Using rizatriptan with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Propranolol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of rizatriptan. Make sure you tell your doctor if you have any other medical problems, especially:

  • Angina (chest pain) or
  • Heart or blood vessel disease or
  • High blood pressure (uncontrolled) or
  • Kidney disease or
  • Liver disease—The chance of side effects may be increased. Heart or blood vessel disease and high blood pressure sometimes do not cause any symptoms, so some people do not know that they have these problems. Before deciding whether you should use rizatriptan, your doctor may need to do some tests to make sure that you do not have any of these conditions

Proper Use of rizatriptan

Take rizatriptan exactly as directed by your doctor. It will work only if taken correctly.

Do not use rizatriptan for a headache that is different from your usual migraines. Instead, check with your doctor.

To relieve your migraine as soon as possible, use rizatriptan as soon as the headache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using rizatriptan.

Lying down in a quiet, dark room for a while after you use rizatriptan may help relieve your migraine.

Ask your doctor ahead of time about any other medicine you may take if rizatriptan does not work. After you take the other medicine, check with your doctor as soon as possible. Headaches that are not relieved by rizatriptan are sometimes caused by conditions that need other treatment.

If you feel much better after a dose of rizatriptan, but your headache comes back or gets worse after a while, you may use more rizatriptan. However, use rizatriptan only as directed by your doctor. Do not use more of it, and do not use it more often, than directed. Using too much rizatriptan may increase the chance of side effects.

Your doctor may direct you to take another medicine to help prevent headaches. It is important that you follow your doctor's directions, even if your headaches continue to occur. Headache-preventing medicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headaches should occur less often, and they should be less severe and easier to relieve. This can reduce the amount of rizatriptan or other pain medicines that you need. If you do not notice any improvement after several weeks of headache-preventing treatment, check with your doctor.

Dosing

The dose of rizatriptan will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of rizatriptan. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets and orally disintegrating tablets):
    • For migraine headaches:
      • Adults—5 or 10 mg as a single dose. If the migraine comes back after being relieved, another dose may be taken two hours after the last dose.
  • Children—Use and dose must be determined by your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using rizatriptan

Drinking alcoholic beverages can make headaches worse or cause new headaches to occur. People who suffer from severe headaches should probably avoid alcoholic beverages, especially during a headache.

Some people feel drowsy or dizzy during or after a migraine, or after taking rizatriptan to relieve a migraine. As long as you are feeling drowsy or dizzy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

rizatriptan Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common
  • Chest pain
  • heaviness, tightness, or pressure in chest and/or neck
  • pounding heartbeat
  • sensation of burning, warmth, heat, numbness, tightness, or tingling
  • shortness of breath
Less common
  • Increased heartbeat
  • irregular heartbeat
  • slow heartbeat
Symptoms of overdose
  • Dizziness
  • fainting
  • headache, severe or continuing
  • sleepiness
  • slow heartbeat
  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Dizziness
  • dry mouth
  • hot flashes
  • nausea and/or vomiting
  • sleepiness
  • unusual tiredness or muscle weakness
Less common
  • Agitation
  • anxiety
  • blurred vision
  • chills
  • confusion
  • constipation
  • depression
  • diarrhea
  • difficulty swallowing
  • dry eyes
  • eye irritation
  • feeling of constant movement of self or surroundings
  • gas
  • headache
  • heartburn
  • heat sensitivity
  • inability to sleep
  • increased sweating
  • increased thirst
  • irritability
  • itching of the skin
  • muscle or joint stiffness, tightness, or rigidity
  • muscle pain or spasms
  • ringing or buzzing in ears
  • sudden large increase in frequency or quantity of urine
  • trembling of hands or feet
  • unusual feeling of well-being
  • warm and/or cold sensations

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

  • Rizatriptan MedFacts Consumer Leaflet (Wolters Kluwer)
  • Maxalt Prescribing Information (FDA)
  • Maxalt Detailed Consumer Information (PDR)
  • Maxalt Consumer Overview
  • Maxalt-MLT Orally Disintegrating Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

See Also...

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