RMS SuppositoriesGeneric Name: Morphine
RMS Suppositories are used for:
Preventing severe pain.
RMS Suppositories are a narcotic pain reliever. It works by dulling the pain perception center in the brain. It may also affect other body systems (eg, respiratory and circulatory systems) at higher doses.
Do NOT use RMS Suppositories if:
- you are allergic to any ingredient in RMS Suppositories
- you have known or suspected paralysis of the intestines or antibiotic-associated colitis
- you have diarrhea due to poisoning
- you are taking cimetidine, sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline), or drink alcohol
- you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days
- you have slowed breathing, increased pressure in the head, a lesion in the head, or recent head injury
- you are having an asthma attack, or have heart failure due to lung disease, arrhythmias, or seizures
- you have had stomach tract surgery
Contact your doctor or health care provider right away if any of these apply to you.
Before using RMS Suppositories:
Some medical conditions may interact with RMS Suppositories. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of substance abuse or dependence, have asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems
- if you have heart, liver, or thyroid diseases; curvature of the spine; or a history of suicidal thoughts or behaviors
- if you have low blood volume, a stomach blockage, or inflammatory bowel disease
Some MEDICINES MAY INTERACT with RMS Suppositories. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Fluoxetine, naltrexone, rifampin, or risperidone because they may decrease RMS Suppositories's effectiveness
- Barbiturate anesthetics (eg, thiopental), cimetidine, ethanol, ketorolac, sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects such as CNS toxicity (disorientation, respiratory depression, seizures) may occur
- Barbiturate anesthetics (eg, thiopental) or sodium oxybate (GHB) because the risk of their side effects may be increased by RMS Suppositories
- Mexiletine or trovafloxacin because their effectiveness may be decreased by RMS Suppositories
This may not be a complete list of all interactions that may occur. Ask your health care provider if RMS Suppositories may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use RMS Suppositories:
Use RMS Suppositories as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Wash your hands before and after using RMS Suppositories. If the suppository is too soft to use, put it in the refrigerator for about 15 minutes. You may also run cold water over it. Remove the wrapper. Moisten the suppository with cool water. Lie down on your side. Insert the pointed end of the suppository into the rectum. Use your finger to push it in completely.
- Take RMS Suppositories on a regular schedule to get the most benefit from it. It is more effective in preventing pain than in treating pain after it occurs.
- If you also take trovafloxacin, do not take it within 4 hours before or after taking RMS Suppositories. Check with your doctor if you have questions.
- If you miss a dose of RMS Suppositories and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regularly dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use RMS Suppositories.
Important safety information:
- RMS Suppositories may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use RMS Suppositories with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using RMS Suppositories; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- RMS Suppositories may cause constipation. Constipation may be avoided by using a stool softener or fiber laxative.
- The risk of RMS Suppositories becoming habit-forming may be greater if you take it in high doses or for a long time. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Tell your doctor or dentist that you take RMS Suppositories before you receive any medical or dental care, emergency care, or surgery.
- Do not take RMS Suppositories if you have had a severe allergic reaction to morphine or hydromorphone (such as MS Contin , Roxanol, Dilaudid). If you have a question about whether you are allergic to RMS Suppositories or if a certain medicine contains morphine or hydromorphone, contact your doctor or pharmacist.
- Lab tests may be performed while you use RMS Suppositories. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use RMS Suppositories with caution in the ELDERLY; they may be more sensitive to its effects.
- RMS Suppositories should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using RMS Suppositories while you are pregnant. RMS Suppositories are found in breast milk. Do not breast-feed while taking RMS Suppositories.
When used for long periods of time or at high doses, RMS Suppositories may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if RMS Suppositories stops working well. Do not take more than prescribed.
Some people who use RMS Suppositories for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking RMS Suppositories suddenly, you may have WITHDRAWAL symptoms. These may include anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.
Possible side effects of RMS Suppositories:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Agitation; blurred vision; constipation; dizziness; drowsiness; exaggerated sense of well-being; feeling disoriented; headache; lightheadedness; nausea; restless mood; sleeplessness; sweating; vision problems; weakness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); bleeding hives; pounding in the chest; seizure; shock; shortness of breath; slow heartbeat; sudden chest pain; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include cold and clammy skin; convulsions; deep sleep; lightheadedness; loss of consciousness; slowed breathing; slowed heart rate.Proper storage of RMS Suppositories:
Store RMS Suppositories between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep RMS Suppositories out of the reach of children and away from pets.
- If you have any questions about RMS Suppositories, please talk with your doctor, pharmacist, or other health care provider.
- RMS Suppositories are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about RMS Suppositories. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
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