Available Dosage Forms:
Therapeutic Class: Anticoagulant
Pharmacologic Class: Thrombin Inhibitor, Direct
Argatroban is used to decrease the clotting ability of the blood and to help prevent harmful clots from forming in the blood vessels. argatroban is used to treat or prevent blood clots in patients with bleeding problems caused by another medicine called heparin. It may also be used in patients who are having certain heart and blood vessel procedures, such as coronary angioplasty.
argatroban is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For argatroban, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to argatroban or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of argatroban in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of argatroban in the elderly. However, elderly patients are more likely to have age-related liver problems, which may require an adjustment of dosage in patients receiving argatroban.
|All Trimesters||B||Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Using argatroban with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using argatroban with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of argatroban. Make sure you tell your doctor if you have any other medical problems, especially:
A nurse or other trained health professional will give you argatroban. argatroban is given through a needle placed into one of your veins.
argatroban will only be given to you while you are in the hospital. Before you leave the hospital, you may be switched to an oral medicine that works in a similar way. If you have any concerns about this, talk to your doctor.
It is very important that your doctor check you at regular visits after you leave the hospital for any problems or unwanted effects that may be caused by argatroban. Be sure to keep all appointments.
argatroban may increase your chance of bleeding. Check with your doctor right away if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin. Avoid picking your nose. If you need to blow your nose, blow it gently.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:More common
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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