Generic Name: sodium hyaluronate (injectable) (SO dee um hi al yoo RON ayt)Brand Names: Euflexxa, Hyalgan, Supartz
Sodium hyaluronate is similar to the synovial (sin-OH-vee-ul) fluid that surrounds your joints. Synovial fluid acts as a lubricant and shock absorber.
Sodium hyaluronate is injected into the knee joint to treat pain caused by osteoarthritis. This medication is usually reserved for people whose pain has not been relieved by using other medicines or treatments.
Sodium hyaluronate may also be used for purposes other than those listed in this medication guide.
Before receiving sodium hyaluronate, tell your doctor if you have an allergy to eggs, birds, or bird products.
Sodium hyaluronate is given as an injection into your knee. This medicine is usually given as one injection per week for a total of 3 weeks.For the first 48 hours after your injection, avoid any strenuous or weight-bearing activity that lasts longer than 1 hour. This includes jogging, tennis, stair-climbing, or lifting weights. Follow your doctor's instructions about other activity restrictions.What should I discuss with my health care provider before receiving sodium hyaluronate?You should not receive sodium hyaluronate if you have:
an infection of your knee joint; or
infection of the skin around your knee.
Before receiving sodium hyaluronate, tell your doctor if you have an allergy to eggs, birds, or bird products.This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether sodium hyaluronate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Sodium hyaluronate is given as an injection into your knee. You will receive this injection in a doctor's office or other clinic setting.
This medicine is usually given as one injection per week for a total of 3 weeks. Your doctor may want you to have injections more often than once each week.
Contact your doctor for instructions if you miss an appointment for your injection.
Seek emergency medical attention if you think you have received too much of this medicine. An overdose of sodium hyaluronate is not expected to produce life-threatening symptoms.
Other less serious side effects are more likely to occur, such as:
pain or swelling where the medicine was injected;
numbness or tingly feeing;
skin irritation; or
knee pain or tenderness.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Osteoarthritis:
Hyalgan(R): 2 mL by intra-articular injection into the knee once weekly for 5 weeksSupartz(TM): 2.5 mL by intra-articular injection into the knee once weekly for 5 weeks
There may be other drugs that can affect sodium hyaluronate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.