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Drugs reference index «Atazanavir»


Generic Name: Atazanavir (A-ta-ZAN-a-vir)Brand Name: Reyataz

Taking Atazanavir with other medicines may result in serious or life-threatening side effects. Ask your doctor or pharmacist if you have any questions about which medicines should not be taken with Atazanavir .

Atazanavir is used for:

Treating HIV infection along with other medicines.

Atazanavir is an HIV protease inhibitor. It works by inhibiting HIV protease, which is the enzyme required to form functional proteins in HIV-infected cells.

Do NOT use Atazanavir if:

  • you are allergic to any ingredient in Atazanavir
  • you are taking certain benzodiazepines (eg, oral midazolam, triazolam), cisapride, an ergot derivative (eg, ergotamine), certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), indinavir, irinotecan, nevirapine, pimozide, rifampin, or St. John's wort
  • you are taking voriconazole and you take ritonavir along with Atazanavir

Contact your doctor or health care provider right away if any of these apply to you.

Before using Atazanavir :

Some medical conditions may interact with Atazanavir . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a blood disorder (eg, hemophilia), diabetes, heart problems (eg, atrioventricular block), or liver problems (including hepatitis B or hepatitis C)
  • if you have kidney problems or are on dialysis

Some MEDICINES MAY INTERACT with Atazanavir . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Certain benzodiazepines (eg, oral midazolam, triazolam), cisapride, ergot derivatives (eg, ergotamine), or pimozide because serious side effects, such as breathing problems, blood vessel problems, or irregular heartbeat may occur
  • Certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin) because the risk of serious muscle effects may be increased
  • Indinavir because it may increase the risk of Atazanavir 's side effects
  • Nevirapine, rifampin or, St. John's wort because they may decrease Atazanavir 's effectiveness
  • Irinotecan because the risk of its side effects may be increased by Atazanavir
  • Many prescription and nonprescription medicines (eg, used for aches and pains, angina, asthma, birth control, blood pressure, blood thinning, cancer, depression, erectile dysfunction, heartburn or reflux disease, immune system suppression, infections, inflammation, irregular heartbeat, heart problems, high blood pressure, high cholesterol, HIV, mental or mood problems, migraine, pain, overactive bladder, seizures, sleep aid), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort ) may interact with Atazanavir , increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Atazanavir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Atazanavir :

Use Atazanavir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Atazanavir . Talk to your pharmacist if you have questions about this information.
  • Take Atazanavir by mouth with food.
  • Swallow Atazanavir whole. Do not break, crush, or chew before swallowing.
  • Take Atazanavir on a regular schedule to get the most benefit from it.
  • Taking Atazanavir at the same time each day will help you remember to take it.
  • If you also take a proton pump inhibitor (eg, omeprazole), take it about 12 hours before you take Atazanavir .
  • If you also take an H2 antagonist (eg, cimetidine), talk with your doctor about how to take it with Atazanavir .
  • If you also take an antacid or didanosine, take Atazanavir at least 2 hours before or 1 hour after the antacid or didanosine.
  • Check with your doctor before you eat grapefruit or drink grapefruit juice while you are taking Atazanavir .
  • Continue to use Atazanavir even if you feel well. Do not miss any doses.
  • If you miss a dose of Atazanavir , take it as soon as possible. If it is within 6 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Atazanavir .

Important safety information:

  • Atazanavir may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Atazanavir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Atazanavir is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
  • When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Atazanavir , even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
  • Atazanavir does not stop the spread of HIV to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
  • Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Atazanavir . The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Atazanavir . To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Atazanavir may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Atazanavir .
  • Atazanavir may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Diabetes patients - Atazanavir may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including liver function tests, bilirubin levels, lipid or cholesterol levels, and electrocardiograms, may be performed while you use Atazanavir . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Atazanavir with caution in the ELDERLY; they may be more sensitive to its effects.
  • Atazanavir should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • Atazanavir should not be used in CHILDREN younger than 3 months old; a type of brain damage caused by high blood bilirubin levels (kernicterus) may occur.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Atazanavir while you are pregnant. It is not known if Atazanavir is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Atazanavir to the baby.

Possible side effects of Atazanavir :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Changes in body fat; cough; diarrhea; fatigue; headache; increased cough; muscle pain; nausea; pain; stomach pain; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; chest pain; dizziness; fever, chills, or sore throat; increased urination or thirst; irregular heartbeat; lightheadedness; mental or mood changes (eg, depression); numbness, tingling, or extreme weakness especially in the arms or legs; painful urination; red, blistered, or swollen skin; severe nausea or vomiting; severe stomach or side pain; trouble breathing; unusual bleeding or bruising; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include severe dizziness and lightheadedness; yellowing of the eyes or skin.

Proper storage of Atazanavir :

Store Atazanavir at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Atazanavir out of the reach of children and away from pets.

General information:

  • If you have any questions about Atazanavir , please talk with your doctor, pharmacist, or other health care provider.
  • Atazanavir is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Atazanavir . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • atazanavir Advanced Consumer (Micromedex) - Includes Dosage Information
  • Reyataz Prescribing Information (FDA)
  • Reyataz Detailed Consumer Information (PDR)
  • Reyataz Consumer Overview

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