Ativan SolutionGeneric Name: Lorazepam
Ativan Solution is used for:
Treating anxiety and causing drowsiness before certain medical procedures and treating certain types of seizures. It may also be prescribed for other conditions as determined by your doctor.
Ativan Solution is a benzodiazepine. It works by slowing down the movement of chemicals in the brain. This results in a reduction in nervous tension (anxiety) and causes sedation.
Do NOT use Ativan Solution if:
- you are allergic to any ingredient in Ativan Solution or any other benzodiazepine (eg, alprazolam)
- you have narrow-angle glaucoma, psychosis, sleep apnea, or severe liver disease
- you are taking sodium oxybate (GHB)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Ativan Solution:
Some medical conditions may interact with Ativan Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are taking any other medicine that causes drowsiness (eg, narcotics, some antidepressants)
- if you have lung function problems, chronic obstructive pulmonary disease (COPD), muscle weakness or fatigue, glaucoma, liver or kidney problems, a blood disorder, depression, or suicidal thoughts
- if you have a history of alcohol or substance abuse or dependence
Some MEDICINES MAY INTERACT with Ativan Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Hydantoins (eg, phenytoin) or theophyllines because they may decrease Ativan Solution's effectiveness
- Clozapine, haloperidol, kava, loxapine, narcotic pain relievers (eg, morphine, codeine), sodium oxybate (GHB), or valproic acid because side effects, such as extreme sedation, slowed breathing, confusion, or memory problems, may occur
- Digoxin, hydantoins (eg, phenytoin), narcotic pain relievers (eg, morphine, codeine), nondepolarizing muscle relaxants (eg, vecuronium), or sodium oxybate (GHB) because the risk of their side effects may be increased by Ativan Solution
- Nondepolarizing muscle relaxants (eg, vecuronium) because they may decrease Ativan Solution's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Ativan Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Ativan Solution:
Use Ativan Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Ativan Solution is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Ativan Solution at home, a health care provider will teach you how to use it. Be sure you understand how to use Ativan Solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use Ativan Solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Ativan Solution should not be injected into an artery because serious side effects may occur.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Ativan Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Ativan Solution.
Important safety information:
- Ativan Solution may cause drowsiness, dizziness, and blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Ativan Solution with caution. Do not drive or perform other possibly unsafe tasks for up to 48 hours after use.
- Do not drink alcohol for at least 24 to 48 hours after using Ativan Solution. Do not use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ativan Solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Effects, such as drowsiness, relief of anxiety, and lack of remembering and recognizing events the day of surgery, will last about 8 hours.
- Other types of sedatives, tranquilizers, and narcotic pain relievers may cause a longer and more intense effect when taken with Ativan Solution. Excessive sleepiness, drowsiness, and memory problems (eg, difficulty remembering and recognizing events the day of and the day after surgery) may occur.
- Do not attempt to get out of bed without help. Trying to get out of bed within 8 hours of receiving Ativan Solution may result in falling or injury.
- Use Ativan Solution with caution in the ELDERLY; they may be more sensitive to its effects.
- Ativan Solution should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Ativan Solution has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ativan Solution while you are pregnant. Ativan Solution is found in breast milk. Do not breast-feed while taking Ativan Solution.
Some people who use Ativan Solution for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.
If you stop taking Ativan Solution suddenly, you may have WITHDRAWAL symptoms. These may include agitation, anxiety, irritability, occasional seizures, or sleeplessness may occur if Ativan Solution is suddenly stopped. If you need to stop Ativan Solution, your doctor will lower your dose over time.
Possible side effects of Ativan Solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Blurred vision; dizziness; dry mouth; excessive sleepiness and drowsiness; headache; pain, swelling, or redness at the injection area; short-term memory loss; weakness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms of overdose may include clumsiness; confusion; deep sleep; loss of consciousness; slow reflexes.Proper storage of Ativan Solution:
Store Ativan Solution in a refrigerator at 36 to 46 degrees F (2 to 8 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Store in original packaging until just before use. Keep Ativan Solution out of the reach of children and away from pets.
- If you have any questions about Ativan Solution, please talk with your doctor, pharmacist, or other health care provider.
- Ativan Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Ativan Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Ativan Prescribing Information (FDA)
- Ativan Consumer Overview
- Ativan Detailed Consumer Information (PDR)
- Ativan Advanced Consumer (Micromedex) - Includes Dosage Information
- Lorazepam Prescribing Information (FDA)
- Lorazepam Professional Patient Advice (Wolters Kluwer)