Tretinoin can cause severe, even fatal, side effects. Therefore, it must be used only under close medical supervision. Notify your doctor immediately if you experience any of the following symptoms: fever, breathing trouble, weight gain, dizziness, chest pain, or unusual fatigue. It may be necessary for your doctor to use other medicines with tretinoin to reduce the chance of side effects. Vesanoid can cause severe birth defects when taken during pregnancy. Therefore, women who are pregnant must be informed of the risk to the fetus from tretinoin use. Women must avoid becoming pregnant while taking Vesanoid . Pregnancy tests should be performed 1 week before starting use of Vesanoid . Women should use 2 forms of contraception (birth control) at the same time, or avoid sexual intercourse, while taking Vesanoid and for 1 month after tretinoin use has been stopped. Women must also have monthly pregnancy testing and birth control counseling from their doctor while taking Vesanoid .
Initiating remission for a certain type of acute promyelocytic leukemia (APL) that has failed to respond to other therapies. It may also be used for other conditions as determined by your doctor.
Vesanoid is a retinoid. How it works in APL is not completely understood. It is thought to decrease the growth of cells associated with APL.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Vesanoid . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Vesanoid . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Vesanoid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Vesanoid as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Vesanoid .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Bone pain; dry skin and mouth; fever; hair loss; headache; increased sweating; itching; nausea; rash; tiredness; vomiting; weakness.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dizziness; hearing loss; heart attack; severe headache; shortness of breath; unusual bruising or bleeding; vision changes; weight gain.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include clumsiness; dizziness; flushing; headache; stomach pain.Proper storage of Vesanoid :
Store Vesanoid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Vesanoid out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Vesanoid . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.