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Drugs reference index «Videx EC Delayed-Release Enteric-Coated Capsules»

Videx EC Delayed-Release Enteric-Coated Capsules


Videx EC Delayed-Release Enteric-Coated Capsules

Generic Name: Didanosine (dye-DAN-oh-seen)Brand Name: Videx EC

Videx EC Delayed-Release Enteric-Coated Capsules may cause serious and sometimes fatal inflammation of the pancreas (pancreatitis). This has occurred in patients who have just started taking Videx EC Delayed-Release Enteric-Coated Capsules and in patients who have already been taking it. Contact your doctor immediately if you experience sudden stomach or back pain, swelling of the stomach, fever or chills, nausea or vomiting, or fast heartbeat.

Videx EC Delayed-Release Enteric-Coated Capsules may cause severe and sometimes fatal lactic acidosis and liver problems. Fatal lactic acidosis has also occurred in pregnant women who have used Videx EC Delayed-Release Enteric-Coated Capsules along with certain other medicines for HIV (eg, stavudine). Tell your doctor if you are taking stavudine and you are pregnant or planning to become pregnant.

Videx EC Delayed-Release Enteric-Coated Capsules are used for:

Treating HIV infection when used in combination with other medicines.

Videx EC Delayed-Release Enteric-Coated Capsules are a nucleoside analogue reverse transcriptase inhibitor that stops the growth of HIV-1, the virus that causes AIDS.

Do NOT use Videx EC Delayed-Release Enteric-Coated Capsules if:

  • you are allergic to any ingredient in Videx EC Delayed-Release Enteric-Coated Capsules
  • you have pancreas problems (pancreatitis), an enlarged liver, abnormal liver function tests, or lactic acidosis
  • you are taking allopurinol or ribavirin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Videx EC Delayed-Release Enteric-Coated Capsules:

Some medical conditions may interact with Videx EC Delayed-Release Enteric-Coated Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of heart problems (eg, heart attack)
  • if you have advanced HIV infection (AIDS), kidney problems, liver problems, gallstones, nerve problems (neuropathy), high blood cholesterol or lipid levels, or high blood amylase levels
  • if you are overweight or you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Videx EC Delayed-Release Enteric-Coated Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Allopurinol, ganciclovir, nucleotide reverse transcriptase inhibitors (eg, tenofovir), or ribavirin because they may increase the risk of Videx EC Delayed-Release Enteric-Coated Capsules's side effects
  • Aluminum salts (eg, aluminum hydroxide) because the risk of their side effects may be increased by Videx EC Delayed-Release Enteric-Coated Capsules
  • Azole antifungals (eg, itraconazole, ketoconazole), delavirdine, HIV protease inhibitors (eg, indinavir, lopinavir, nelfinavir), lithium, quinolones (eg, ciprofloxacin, levofloxacin), sulfones (eg, dapsone), or tetracyclines (eg, doxycycline) because their effectiveness may be decreased by Videx EC Delayed-Release Enteric-Coated Capsules
  • Hydroxyurea because the risk of pancreatitis may be increased
  • Methadone because it may decrease Videx EC Delayed-Release Enteric-Coated Capsules's effectiveness
  • Stavudine because the risk of pancreatitis or fatal lactic acidosis in pregnant women may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Videx EC Delayed-Release Enteric-Coated Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Videx EC Delayed-Release Enteric-Coated Capsules:

Use Videx EC Delayed-Release Enteric-Coated Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Videx EC Delayed-Release Enteric-Coated Capsules. Talk to your pharmacist if you have questions about this information.
  • Take Videx EC Delayed-Release Enteric-Coated Capsules by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
  • Swallow Videx EC Delayed-Release Enteric-Coated Capsules whole. Do not break, crush, or chew before swallowing.
  • Videx EC Delayed-Release Enteric-Coated Capsules may reduce the effectiveness of certain other medicines when taken together. Ask your doctor or pharmacist if you should separate Videx EC Delayed-Release Enteric-Coated Capsules from any other medicine that you are taking.
  • Continue to take Videx EC Delayed-Release Enteric-Coated Capsules even if you feel well. Do not miss any doses.
  • If you miss a dose of Videx EC Delayed-Release Enteric-Coated Capsules, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. It is important not to miss doses of Videx EC Delayed-Release Enteric-Coated Capsules. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Videx EC Delayed-Release Enteric-Coated Capsules.

Important safety information:

  • Do not drink alcohol while you are taking Videx EC Delayed-Release Enteric-Coated Capsules.
  • Videx EC Delayed-Release Enteric-Coated Capsules are not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
  • Videx EC Delayed-Release Enteric-Coated Capsules does not stop the spread of HIV to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
  • When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Videx EC Delayed-Release Enteric-Coated Capsules, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
  • Tell your doctor or dentist that you take Videx EC Delayed-Release Enteric-Coated Capsules before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including eye exams, may be performed while you use Videx EC Delayed-Release Enteric-Coated Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Videx EC Delayed-Release Enteric-Coated Capsules with caution in the ELDERLY; they may be more sensitive to its effects.
  • Use Videx EC Delayed-Release Enteric-Coated Capsules with extreme caution in CHILDREN weighing less than 44 lbs; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Videx EC Delayed-Release Enteric-Coated Capsules while you are pregnant. It is not known if Videx EC Delayed-Release Enteric-Coated Capsules are found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Videx EC Delayed-Release Enteric-Coated Capsules to the baby.

Possible side effects of Videx EC Delayed-Release Enteric-Coated Capsules:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Breast enlargement; changes in body fat; darkened complexion with purple markings; diarrhea; dry mouth; headache; itching; muscle pain; skin and facial wasting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; chest pain or discomfort, numbness of an arm or leg, or shortness of breath; confusion; dark urine; dizziness; fainting; fast, shallow breathing; fast, slow, or irregular heartbeat; fever or chills; lightheadedness; low body temperature; nausea or vomiting; numbness, tingling, or pain in hands or feet; seizures; severe muscle pain or cramping; stomach pain; tiredness; weakness; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; diarrhea; pale stools; severe stomach pain with nausea and vomiting; tingling, burning, or numbness in hands or feet; unusual fatigue; yellowing of skin or eyes.

Proper storage of Videx EC Delayed-Release Enteric-Coated Capsules:

Store Videx EC Delayed-Release Enteric-Coated Capsules at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in a tightly closed container. Brief storage up to 86 degrees F (30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Videx EC Delayed-Release Enteric-Coated Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Videx EC Delayed-Release Enteric-Coated Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Videx EC Delayed-Release Enteric-Coated Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Videx EC Delayed-Release Enteric-Coated Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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