Abacavir SolutionGeneric Name:
Abacavir (a-BAK-a-vir)Brand Name:
Abacavir Solution has caused severe and sometimes fatal allergic reactions. Contact your doctor right away if you develop fever; rash; nausea, vomiting, diarrhea, or stomach pain; cough; sore throat, or trouble breathing; unusual tiredness or achiness; or general feeling of being unwell. Do NOT take Abacavir Solution again or take any other medicine that contains abacavir if you have had an allergic reaction to Abacavir Solution. You may be at risk for an even more severe allergic reaction.
Patients who have a certain gene type called HLA-B*5701 have an increased risk of allergic reaction. A lab test may be performed before you start Abacavir Solution to see if you have this gene type. Discuss any questions or concerns with your doctor.
Abacavir Solution may cause severe and sometimes fatal liver problems or high blood acid levels (lactic acidosis). Contact your doctor right away if you develop yellowing of the skin or eyes; dark urine; pale stools; stomach pain; nausea; vomiting; diarrhea; persistent loss of appetite; fast or difficult breathing; slow or irregular heartbeat; unusual weakness or tiredness; muscle pain or tenderness; unusual feeling of cold (eg, in arms or legs); or unusual drowsiness, dizziness, or lightheadedness.
Abacavir Solution is used for:
Treating HIV infection with other medications.
Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI). It works by slowing down the growth of HIV, the virus that causes AIDS.
Do NOT use Abacavir Solution if:
- you are allergic to any ingredient in Abacavir Solution
- you have had a recent abnormal liver function test or have moderate to severe liver problems
Contact your doctor or health care provider right away if any of these apply to you.
Before using Abacavir Solution:
Some medical conditions may interact with Abacavir Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding or thinking about breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of heart problems (eg, heart attack), high blood pressure, high cholesterol, diabetes, or smoking
- if you have been tested and know whether or not you have a gene type called HLA-B*5701
Some MEDICINES MAY INTERACT with Abacavir Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Alcohol because it may increase the risk of Abacavir Solution's side effects and toxic effects
- Methadone because its effectiveness may be decreased by Abacavir Solution
This may not be a complete list of all interactions that may occur. Ask your health care provider if Abacavir Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Abacavir Solution:
Use Abacavir Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Abacavir Solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Abacavir Solution refilled.
- Abacavir Solution comes with a warning card that provides information about recognition of allergic reactions. Carry the warning card of allergy symptoms with you. Tell your health care provider immediately about any side effects you experience while taking Abacavir Solution.
- Take Abacavir Solution by mouth with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Taking Abacavir Solution at the same times each day will help you to remember to take it. Continue to take Abacavir Solution even if you feel well. Do not miss any doses.
- If you miss a dose of Abacavir Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Abacavir Solution.
Important safety information:
- Talk to your doctor before you take Abacavir Solution if you drink more than 3 drinks with alcohol per day.
- Tell your doctor or dentist that you take Abacavir Solution before you receive any medical or dental care, emergency care, or surgery.
- If you must stop taking Abacavir Solution for any reason other than a serious allergic reaction, do not start taking Abacavir Solution again without talking with your health care provider. If your health care provider decides that you may take Abacavir Solution again, you should do so only in a setting with other people in case you need immediate access to a doctor.
- When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Abacavir Solution, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
- Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Abacavir Solution. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.
- Abacavir Solution does not stop the spread of HIV to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
- Abacavir Solution is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
- Lab tests, including liver function tests and monitoring for hypersensitivity reactions, may be performed while you use Abacavir Solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Abacavir Solution with caution in the ELDERLY; they may be more sensitive to its effects, especially liver, kidney, or heart problems.
- Caution is advised when using Abacavir Solution in CHILDREN; they may be more sensitive to its effects, especially fever; chills; rash; or ear, nose, or throat infection.
- Abacavir Solution should not be used in CHILDREN younger than 3 months old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Abacavir Solution while you are pregnant. It is not known if Abacavir Solution is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Abacavir Solution to the baby.
Possible side effects of Abacavir Solution:
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Headache; lack of energy; mild nausea; tiredness; trouble sleeping; unusual dreams; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, numbness, or tingling of the skin; change in the amount of urine produced; chest pain or discomfort, numbness of an arm or leg, or sudden vision changes; ear pain; eye pain, redness, or swelling; fainting; fever or chills; general feeling of being unwell; mental or mood changes (eg, depression); mouth sores; red, swollen, blistered, or peeling skin; severe or persistent dizziness; severe or persistent nausea, vomiting, or diarrhea; shortness of breath, cough, or sore throat; stomach pain; swollen lymph nodes; symptoms of lactic acidosis (eg, fast breathing; muscle pain; unusual cold feeling in the arms or legs; sluggishness; unusual drowsiness, dizziness, or lightheadedness); symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, loss of appetite, severe or persistent tiredness); unusual achiness or swelling.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Abacavir Solution:
Store Abacavir Solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Abacavir Solution out of the reach of children and away from pets.
- If you have any questions about Abacavir Solution, please talk with your doctor, pharmacist, or other health care provider.
- Abacavir Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is summary only. It does not contain all information about Abacavir Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
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