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Drugs reference index «azithromycin Intravenous»

azithromycin (Intravenous route)

ay-zith-roe-MYE-sin

Commonly used brand name(s):

In the U.S.

  • Zithromax

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Antibiotic

Chemical Class: Macrolide

Uses For azithromycin

Azithromycin injection is used to treat bacterial infections in many different parts of the body. It is also used to prevent Mycobacterium avium complex (MAC) disease in patients infected with the human immunodeficiency virus (HIV).

Azithromycin injection belongs to the class of drugs known as macrolide antibiotics. It works by killing bacteria or preventing their growth. However, azithromycin will not work for colds, flu, or other viral infections. Azithromycin injection may be used for other problems as determined by your doctor.

Azithromycin injection is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, azithromycin is used in certain patients with the following medical condition:

  • Trachoma (treatment)

Before Using azithromycin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For azithromycin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to azithromycin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of azithromycin injection in children and teenagers below 16 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of azithromycin injection in the elderly. However, elderly patients are more likely to have age-related heart problems, which may require caution in patients receiving azithromycin injection.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Using azithromycin with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Dihydroergotamine
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Methylergonovine
  • Methysergide
  • Pimozide

Using azithromycin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acecainide
  • Amiodarone
  • Azimilide
  • Bretylium
  • Disopyramide
  • Dofetilide
  • Ibutilide
  • Propafenone
  • Sematilide
  • Sotalol
  • Tedisamil

Using azithromycin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Atorvastatin
  • Digoxin
  • Fentanyl
  • Lovastatin
  • Nelfinavir
  • Rifabutin
  • Simvastatin
  • Theophylline
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of azithromycin. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart rhythm problems (e.g., prolonged QT interval), history of—Use with caution. May make these condition worse.
  • Kidney disease or
  • Liver disease—Effects may be increased because of slower removal of the medicine from the body. .

Proper Use of azithromycin

A nurse or other trained health professional will give you azithromycin. azithromycin is given through a needle placed in one of your veins.

Your doctor may give you a few doses of azithromycin until your condition improves, and then you may be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Precautions While Using azithromycin

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

azithromycin may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash; itching; hives; hoarseness; shortness of breath; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after you receive azithromycin.

Azithromycin injection may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Tell your doctor if you have bleeding, blistering, burning, discoloration of skin, itching, lumps, pain, rash, redness, swelling, at the site of injection.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

azithromycin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Pain, redness, and swelling at the site of injection
Rare
  • Abdominal or stomach cramps or pain (severe)
  • abdominal tenderness
  • diarrhea (watery and severe, which may be bloody)
  • difficulty in breathing
  • fever
  • joint pain
  • skin rash
  • swelling of the face, mouth, neck, hands, and feet

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Diarrhea (mild)
  • nausea
  • stomach pain or discomfort
Rare
  • Dizziness
  • headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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