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Drugs reference index «Bendamustine»


Generic Name: Bendamustine (BEN-da-MUS-teen)Brand Name: Treanda

Bendamustine is used for:

Treating chronic lymphocytic leukemia (CLL). It is also used to treat a certain type of non-Hodgkin lymphoma (NHL) in certain patients. It may also be used for other conditions as determined by your doctor.

Bendamustine is an alkylating agent. It works by blocking the growth of cancer cells.

Do NOT use Bendamustine if:

  • you are allergic to any ingredient in Bendamustine (including mannitol)
  • you have moderate to severe liver problems
  • you have severe kidney problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Bendamustine :

Some medical conditions may interact with Bendamustine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances (eg, mannitol)
  • if you have an infection, liver or kidney problems, other types of cancer, or bone marrow depression
  • if you smoke or have a history of tobacco use

Some MEDICINES MAY INTERACT with Bendamustine . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Ciprofloxacin or fluvoxamine because they may increase the risk of Bendamustine 's side effects
  • Omeprazole because it may decrease Bendamustine 's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bendamustine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bendamustine :

Use Bendamustine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Bendamustine is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Bendamustine at home, a health care provider will teach you how to use it. Be sure you understand how to use Bendamustine . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Bendamustine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • If Bendamustine accidentally spills on your skin, wash it off right away with soap and water.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Bendamustine , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Bendamustine .

Important safety information:

  • Bendamustine may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Bendamustine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Bendamustine may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.
  • If you may become pregnant, you must use an effective form of birth control while you receive Bendamustine and for 3 months after you stop it. If you have questions about effective birth control, talk with your doctor.
  • Men who take Bendamustine should always use a condom when having sex with a woman who may become pregnant. Do this for as long as you take Bendamustine and for 3 months after you stop taking it.
  • Bendamustine may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
  • Check with your doctor before having immunizations (vaccinations) while you are using Bendamustine .
  • Tell your doctor or dentist that you take Bendamustine before you receive any medical or dental care, emergency care, or surgery.
  • Use of Bendamustine may increase your risk of developing another cancer. Discuss any questions or concerns with your doctor.
  • Lab tests, including blood chemistry, uric acid levels, complete blood cell counts, or liver or kidney function, may be performed while you use Bendamustine . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Bendamustine should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Bendamustine may cause harm to the fetus. Avoid becoming pregnant while you are using Bendamustine and for 3 months after you stop Bendamustine . If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Bendamustine while you are pregnant. It is not known if Bendamustine is found in breast milk. Do not breast-feed while taking Bendamustine .

Possible side effects of Bendamustine :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; cough; diarrhea; drowsiness; dry mouth; headache; loss of appetite; mild fever; mild itching, pain, redness, or swelling at the injection site; mouth sores; nausea; stomach pain; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; decreased urination; fast or irregular heartbeat; fever, chills, or persistent sore throat; persistent or severe cough; redness, swelling, peeling, or blistering of the skin; severe or persistent tiredness or weakness; shortness of breath; unusual bruising or bleeding; unusual swelling; unusual weight loss.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include irregular heartbeat; loss of coordination; seizures; severe drowsiness; tremor; trouble breathing.

Proper storage of Bendamustine :

Bendamustine is usually handled and stored by a health care provider. If you are using Bendamustine at home, store Bendamustine as directed by your pharmacist or health care provider. Keep Bendamustine out of the reach of children and away from pets.

General information:

  • If you have any questions about Bendamustine , please talk with your doctor, pharmacist, or other health care provider.
  • Bendamustine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Bendamustine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • bendamustine Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information
  • Treanda Prescribing Information (FDA)
  • Treanda Consumer Overview

See Also...

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