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Drugs reference index «Acetaminophen/Pamabrom/Pyrilamine»


Generic Name: Acetaminophen/Pamabrom/Pyrilamine (a-SEET-a-MIN-oh-fen/PAM-a-brom/pir-IL-a-meen)Brand Name: Examples include Menstrual PMS and Midol PMS

Acetaminophen/Pamabrom/Pyrilamine is used for:

Treating symptoms associated with menstrual periods, such as muscle aches, cramps, bloating, headache, fatigue, breast tenderness, and water weight gain.

Acetaminophen/Pamabrom/Pyrilamine is an analgesic, antihistamine, and mild diuretic combination. The analgesic and antihistamine work in the brain to help reduce aches, pain, and discomfort associated with the menstrual period. The diuretic helps you to get rid of excess water to help relieve bloating and water weight gain.

Do NOT use Acetaminophen/Pamabrom/Pyrilamine if:

  • you are allergic to any ingredient in Acetaminophen/Pamabrom/Pyrilamine
  • you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Acetaminophen/Pamabrom/Pyrilamine :

Some medical conditions may interact with Acetaminophen/Pamabrom/Pyrilamine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of alcohol abuse or you drink more than 3 alcohol-containing drinks every day
  • if you have hepatitis, liver or kidney problems, lung or breathing problems (eg, asthma, emphysema or chronic bronchitis), increased pressure in the eye, glaucoma, a blockage of your bladder, prostate problems, or trouble urinating
  • if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or medicines that may damage the liver; ask your doctor or pharmacist if you are unsure if you take these types of medicines

Some MEDICINES MAY INTERACT with Acetaminophen/Pamabrom/Pyrilamine . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because severe drowsiness and prolonged sleep duration may occur
  • Anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Acetaminophen/Pamabrom/Pyrilamine
  • Isoniazid because the risk of liver problems may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetaminophen/Pamabrom/Pyrilamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Acetaminophen/Pamabrom/Pyrilamine :

Use Acetaminophen/Pamabrom/Pyrilamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Acetaminophen/Pamabrom/Pyrilamine by mouth with or without food.
  • If you miss a dose of Acetaminophen/Pamabrom/Pyrilamine and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetaminophen/Pamabrom/Pyrilamine .

Important safety information:

  • Acetaminophen/Pamabrom/Pyrilamine may cause drowsiness. This effect may be worse if you take it with alcohol or certain medicines. Use Acetaminophen/Pamabrom/Pyrilamine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Acetaminophen/Pamabrom/Pyrilamine ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Check with your doctor if your pain symptoms do not get better within 10 days, if they get worse, or if new symptoms occur.
  • Acetaminophen/Pamabrom/Pyrilamine has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Acetaminophen/Pamabrom/Pyrilamine may harm your liver. Your risk may be greater if you drink alcohol while you are using Acetaminophen/Pamabrom/Pyrilamine . Talk to your doctor before you take Acetaminophen/Pamabrom/Pyrilamine or other fever reducers if you drink more than 3 drinks with alcohol per day.
  • Caution is advised when using Acetaminophen/Pamabrom/Pyrilamine in CHILDREN; they may be more sensitive to its effects, especially excitability.
  • Check with your child's doctor before giving Acetaminophen/Pamabrom/Pyrilamine to a CHILD younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acetaminophen/Pamabrom/Pyrilamine while you are pregnant. It is not known if Acetaminophen/Pamabrom/Pyrilamine is found in breast milk. If you are or will be breast-feeding while you use Acetaminophen/Pamabrom/Pyrilamine , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Acetaminophen/Pamabrom/Pyrilamine :

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:


Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine or pale stools; severe or persistent stomach pain; unusual fatigue; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; excessive sweating; extreme fatigue; nausea and vomiting; stomach pain.

Proper storage of Acetaminophen/Pamabrom/Pyrilamine :

Store Acetaminophen/Pamabrom/Pyrilamine at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetaminophen/Pamabrom/Pyrilamine out of the reach of children and away from pets.

General information:

  • If you have any questions about Acetaminophen/Pamabrom/Pyrilamine , please talk with your doctor, pharmacist, or other health care provider.
  • Acetaminophen/Pamabrom/Pyrilamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Acetaminophen/Pamabrom/Pyrilamine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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