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Drugs reference index «Benzamycin»



Generic name: Erythromycin, Benzoyl peroxideBrand names: Benzamycin

Why is Benzamycin prescribed?

A combination of the antibiotic erythromycin and the antibacterial agent benzoyl peroxide, Benzamycin is effective in stopping the bacteria that cause acne and in reducing acne infection.

Most important fact about Benzamycin

If you experience excessive irritation, stop using Benzamycin and notify your doctor.

How should you take Benzamycin?

Use Benzamycin 2 times per day, once in the morning and once in the evening, or as directed by your doctor.

Before applying Benzamycin, thoroughly wash the affected area with soap and warm water, rinse well, and gently pat dry. Apply Benzamycin to the entire area, not just the pimples.

  • If you miss a dose...Apply it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.
  • Storage instructions...This medication should be stored in your refrigerator in a tightly closed container and discarded after 3 months. Do not freeze.

What side effects may occur?

Very few side effects have been reported with the use of Benzamycin. However, those reported include dryness and swelling. Occasionally, use of Benzamycin has caused a burning sensation; eye irritation; inflammation of the face, eyes, and nose; itching; oiliness; reddened skin; skin discoloration; skin irritation and peeling; and skin tenderness.

If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Benzamycin.

Why should Benzamycin not be prescribed?

If you are sensitive to or have ever had an allergic reaction to erythromycin or benzoyl peroxide, or any other ingredients in Benzamycin, you should not use Benzamycin. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Benzamycin

Benzamycin Topical Gel is for external use only. Avoid contact with your eyes, nose, mouth, and all mucous membranes.

Benzamycin may bleach hair or colored fabric. Avoid contact with scalp and clothes.

As you use this antibiotic, organisms that are resistant to it may start to grow. Your doctor will have you stop using Benzamycin and will give you a medication to fight the new bacteria.

If you develop diarrhea after you start using Benzamycin, call your doctor. You may have an intestinal inflammation that could be serious.

Possible food and drug interactions when taking Benzamycin

If Benzamycin is used with other acne medications, the effects of either could be increased, decreased, or altered. Always check with your doctor before combining any other prescription or over-the-counter acne remedy with Benzamycin.

Special information if you are pregnant or breastfeeding

The effects of Benzamycin during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether Benzamycin appears in breast milk, but erythromycin does if it is swallowed or injected. If Benzamycin is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment with Benzamycin is finished.

Recommended dosage for Benzamycin


Apply to affected areas twice daily, once in the morning and once in the evening.


The safety and effectiveness of Benzamycin have not been established in children under 12 years of age.


There is no information available on overdosage.

  • Benzamycin Concise Consumer Information (Cerner Multum)
  • Benzamycin Gel MedFacts Consumer Leaflet (Wolters Kluwer)
  • Benzamycin Pak Prescribing Information (FDA)
  • Benzamycin Pak Topical Advanced Consumer (Micromedex) - Includes Dosage Information

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