Bexarotene GelGeneric Name:
Bexarotene (beks-AIR-oh-teen)Brand Name:
Bexarotene Gel is used for:
Treating skin lesions in patients with cutaneous T-cell lymphoma (CTCL). It may also be used for other conditions as determined by your doctor.
Bexarotene Gel is a retinoid. Exactly how it works is unknown.
Do NOT use Bexarotene Gel if:
- you are allergic to any ingredient in Bexarotene Gel
- you are pregnant or breast-feeding
Contact your doctor or health care provider right away if any of these apply to you.
Before using Bexarotene Gel:
Some medical conditions may interact with Bexarotene Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are planning to become pregnant
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are allergic to other retinoids (eg, tretinoin)
- if you have liver or kidney problems
Some MEDICINES MAY INTERACT with Bexarotene Gel. Because little, if any, of Bexarotene Gel is absorbed into the blood, the risk of it interacting with another medicine is low.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Bexarotene Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Bexarotene Gel:
Use Bexarotene Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Bexarotene Gel is for external use only. Avoid getting Bexarotene Gel in your eyes, nose, or mouth. If you get Bexarotene Gel in your eyes, rinse thoroughly with water.
- Wash your hands before and after using Bexarotene Gel unless your hands are part of the treatment area.
- Apply a generous coating of Bexarotene Gel to the entire lesion. Avoid getting Bexarotene Gel on the healthy skin around the lesions. Allow Bexarotene Gel to dry before covering it with cloth.
- Do not bandage or wrap Bexarotene Gel unless instructed to do so by your doctor.
- Continue to use Bexarotene Gel even if you feel well. Do not miss any doses.
- If you miss a dose of Bexarotene Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Bexarotene Gel.
Important safety information:
- Bexarotene Gel may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Bexarotene Gel. Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
- Do not use products that contain DEET (eg, insect repellant) while you are using Bexarotene Gel.
- Do not exceed the recommended dose or use Bexarotene Gel for longer than prescribed without checking with your doctor.
- Talk to your doctor before taking vitamin A supplements or multivitamins that contain vitamin A.
- During sexual intercourse with a woman who may become pregnant, men taking Bexarotene Gel should use a condom during treatment with Bexarotene Gel and for at least 30 days after it is stopped.
- Women using Bexarotene Gel must have a negative pregnancy test within 1 week prior to beginning therapy with Bexarotene Gel, and each month after that until therapy is finished. Begin therapy with Bexarotene Gel on the second and third day of a normal menstrual period. Use 2 effective forms of birth control during treatment with Bexarotene Gel and for at least 30 days after it is stopped.
- Bexarotene Gel may be harmful if swallowed. If you or someone you know may have taken Bexarotene Gel by mouth, contact your local poison control center or emergency room immediately.
- Use Bexarotene Gel with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use Bexarotene Gel if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if this excreted in breast milk. Do not breast-feed while you are using Bexarotene Gel.
Possible side effects of Bexarotene Gel:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Headache; pain or itching at the application site.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever, chills, or sore throat; irritation at the application site; numbness or tingling of the skin; swelling.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Bexarotene Gel:
Store Bexarotene Gel at 77 degrees F (25 degrees C). Brief storage at temperature between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bexarotene Gel out of the reach of children and away from pets.
- If you have any questions about Bexarotene Gel, please talk with your doctor, pharmacist, or other health care provider.
- Bexarotene Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Bexarotene Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- Bexarotene Professional Patient Advice (Wolters Kluwer)
- bexarotene Concise Consumer Information (Cerner Multum)
- bexarotene Advanced Consumer (Micromedex) - Includes Dosage Information
- Targretin Prescribing Information (FDA)