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Drugs reference index «Biltricide»

Biltricide
Biltricide


Biltricide

Generic Name: praziquantel (Oral route)

praz-i-KWON-tel

Commonly used brand name(s):

In the U.S.

  • Biltricide

Available Dosage Forms:

  • Tablet

Therapeutic Class: Anthelmintic

Uses For Biltricide

Praziquantel belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Praziquantel is used to treat blood fluke infections. These are also known as snail fever, schistosomiasis , or bilharziasis. Praziquantel may also be used for other worm infections as determined by your doctor. However, it will not work for pinworms or other roundworms.

Praziquantel works by causing severe spasms and paralysis of the worms' muscles. Some kinds of worms are then passed in the stool. However, you may not notice them since they are sometimes completely destroyed in the intestine.

Praziquantel is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, praziquantel is used in certain patients with the following medical conditions:

  • Some kinds of fluke infections
  • Some kinds of tapeworm infections

Before Using Biltricide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in a limited number of children 4 years of age or older and, in effective doses, has not been reported to cause different side effects or problems in children over 4 years of age than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of praziquantel in the elderly with use in other age groups.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Rifampin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Carbamazepine
  • Chloroquine
  • Fosphenytoin
  • Ketoconazole
  • Phenytoin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart disease—Your doctor may want to check you heart while using this medicine.
  • Liver disease—Patients with moderate to severe liver disease may have an increased chance of side effects
  • Worm cysts in the brain—Your doctor may want you in the hospital to treat this infection.
  • Worm cysts in the eye—The death of worm cysts in the eye caused by praziquantel may cause damage to the eyes

Proper Use of Biltricide

No special preparations (for example, special diets, fasting, other medicines, laxatives, or enemas) are necessary before, during, or immediately after taking praziquantel.

Praziquantel has a bitter taste that may cause gagging or vomiting. The bitter taste may be more noticeable if the tablets are held in the mouth or chewed. Therefore, do not chew praziquantel tablets. Swallow them whole with a small amount of liquid during meals.

To help clear up your infection completely, take this medicine exactly as directed by your doctor for the full time of treatment. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For the treatment of clonorchiasis (Chinese or Oriental liver fluke) and opisthorchiasis (liver flukes):
    • Adults and children 4 years of age and older: Dose is based on body weight and will be determined by your doctor. This dose is taken three times a day for one day.
    • Children up to 4 years of age: Dose must be determined by the doctor.
  • For the treatment of schistosomiasis:
    • Adults and children 4 years of age and older: Dose is based on body weight and will be determined by your doctor. This dose is taken three times a day for one day.
    • Children up to 4 years of age: Dose must be determined by the doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Each dose should be at least 4 hours apart and not more than 6 hours apart.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Biltricide

It is important that your doctor check your progress after treatment. This is to make sure that the infection is cleared up completely.

If your symptoms do not improve after you have taken this medicine for the full time of treatment, or if they become worse, check with your doctor.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. If any of these side effects occur, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert while you are taking praziquantel and for 24 hours after you stop taking it.

Biltricide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Incidence not known
  • chest pain or discomfort
  • fainting
  • fast, slow, or irregular heartbeat
  • hives
  • hoarseness
  • itching
  • irritation
  • joint pain, stiffness, or swelling
  • lightheadedness
  • rash
  • redness of skin
  • seizures
  • severe abdominal pain
  • shortness of breath
  • swelling of eyelids, face, lips, hands, or feet
  • tightness in chest
  • troubled breathing or swallowing
  • unusual tiredness
  • wheezing

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Abdominal or stomach cramps or pain
  • bloody diarrhea
  • dizziness
  • drowsiness
  • fever
  • headache
  • increased sweating
  • loss of appetite
  • general feeling of discomfort or illness
  • nausea or vomiting
Less common
  • Skin rash, hives, or itching
Incidence not known
  • dizziness or lightheadedness
  • feeling of constant movement of self or surroundings
  • lack or loss of strength
  • sensation of spinning
  • sleepiness or unusual drowsiness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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  • Biltricide Prescribing Information (FDA)
  • Biltricide Concise Consumer Information (Cerner Multum)
  • Biltricide MedFacts Consumer Leaflet (Wolters Kluwer)
  • Praziquantel Professional Patient Advice (Wolters Kluwer)

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