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Drugs reference index «Bonine»



Generic name: Meclizine hydrochlorideBrand names: Bonine, Antivert

Why is Bonine prescribed?

Antivert, an antihistamine, is prescribed for the management of nausea, vomiting, and dizziness associated with motion sickness.

Antivert may also be prescribed for the management of vertigo (a spinning sensation or a feeling that the ground is tilted) due to diseases affecting the vestibular system (the bony labyrinth of the ear, which contains the sensors that control your balance).

Most important fact about Bonine

Antivert may cause you to become drowsy or less alert; therefore, driving a car or operating dangerous machinery is not recommended.

How should you take Bonine?

Take Bonine exactly as prescribed by your doctor.

  • If you miss a dose...Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.
  • Storage instructions...Store away from heat, light, and moisture.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Antivert.

  • Side effects may include:Drowsiness, dry mouth

Why should Bonine not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Antivert or similar drugs, do not take Bonine. Make sure that your doctor is aware of any drug reactions you have experienced.

Special warnings about Bonine

If you have asthma, glaucoma, or an enlarged prostate gland, check with your doctor before using Antivert.

Possible food and drug interactions when taking Bonine

Antivert may intensify the effects of alcohol. Do not drink alcohol while taking Bonine.

Special information if you are pregnant or breastfeeding

Studies regarding the use of Antivert in pregnant women do not indicate that Bonine increases the risk of abnormalities. However, if you are pregnant or plan to become pregnant, inform your doctor before using Antivert. Check with him, too, if you are breastfeeding your baby.

Recommended dosage for Bonine


Motion Sickness:

For protection against motion sickness, take 25 to 50 milligrams 1 hour before traveling. You may repeat the dose every 24 hours for the duration of the journey.


The recommended dosage is 25 to 100 milligrams per day, divided into equal, smaller doses as determined by your doctor.


The safety and effectiveness of Antivert have not been established in children under 12 years of age.


Any medication taken in excess can have serious consequences. If you suspect an overdose of Antivert, seek emergency medical treatment immediately.

  • Meclizine Prescribing Information (FDA)
  • Meclizine Professional Patient Advice (Wolters Kluwer)
  • Antivert MedFacts Consumer Leaflet (Wolters Kluwer)
  • Antivert Prescribing Information (FDA)
  • Antivert Consumer Overview

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