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Drugs reference index «brinzolamide Ophthalmic»

brinzolamide Ophthalmic
brinzolamide Ophthalmic


brinzolamide (Ophthalmic route)

brin-ZOE-la-mide

Commonly used brand name(s):

In the U.S.

  • Azopt

In Canada

  • Azopt 1%

Available Dosage Forms:

  • Suspension

Therapeutic Class: Antiglaucoma

Pharmacologic Class: Carbonic Anhydrase Inhibitor

Uses For brinzolamide

Brinzolamide is a carbonic anhydrase inhibitor that is used in the eye. It is used to treat increased pressure in the eye caused by open-angle glaucoma. It is also used to treat a condition called hypertension of the eye.

brinzolamide is available only with your doctor's prescription.

Before Using brinzolamide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For brinzolamide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to brinzolamide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on brinzolamide have been done only in adult patients and there is no specific information comparing use of brinzolamide in children with use in other age groups.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of brinzolamide. Make sure you tell your doctor if you have any other medical problems, especially:

  • Kidney disease, severe or
  • Liver disease—Effects of ophthalmic brinzolamide may be increased because of slower removal from the body

Proper Use of brinzolamide

brinzolamide should be shaken before each use.

To use: First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye. Immediately after using the eye drops, wash your hands to remove any medicine that may be on them. To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

Use brinzolamide only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects.

If your doctor ordered two different eye drops to be used together, wait at least 10 minutes between the times you apply the medicines. This will help to keep the second medicine from “washing out” the first one.

Dosing

The dose of brinzolamide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of brinzolamide. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For ophthalmic dosage form (eye drops):
    • For glaucoma or hypertension of the eye:
      • Adults—Use 1 drop in the eye three times a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of brinzolamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using brinzolamide

It is important that your doctor check your progress at regular visits to make sure that brinzolamide is working properly and is not causing unwanted effects.

If itching, redness, swelling, or other signs of eye or eyelid irritation occur, check with your doctor. These signs may mean that you are allergic to ophthalmic brinzolamide.

The preservative used in these eye drops may be absorbed by soft contact lenses and cause irritation of your eyes. Soft contact lenses should be taken out before you use brinzolamide eye drops. Lenses may be put back in the eyes 15 minutes after you have used the medicine.

Check with your doctor if you get an injury or infection in your eye or if you are scheduled to have eye surgery. Your doctor may want you to use a fresh bottle of brinzolamide eye drops in case the present bottle of eye drops has become contaminated during use.

brinzolamide may cause some people to have blurred vision for a short time after each use. Make sure you know how you react to brinzolamide before you drive, use machines, or do anything else that could be dangerous if you cannot see properly.

brinzolamide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common
  • Discharge from the eye
  • feeling of something in the eye
  • headache
  • redness, soreness, irritation, or pain of eye or eyelid
  • skin rash
Rare
  • Chest pain
  • dizziness
  • excessive muscle tone
  • hair loss
  • hives
  • kidney pain
  • itching, swelling, or other signs of eye or eyelid irritation
  • seeing double
  • shortness of breath
  • sore throat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Bitter, sour, or other unusual taste
  • blurred vision for a short time after use of medicine
Less common
  • Burning, stinging, or discomfort when medicine is applied
  • dry eye
  • runny nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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  • brinzolamide ophthalmic Concise Consumer Information (Cerner Multum)
  • Azopt Prescribing Information (FDA)
  • Azopt Drops MedFacts Consumer Leaflet (Wolters Kluwer)

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