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Drugs reference index «C1 Esterase Inhibitor (Human)»

C1 Esterase Inhibitor (Human)

Generic Name: C1 Esterase Inhibitor (Human) (C1 ES-ter-ase in-HIB-i-ter)Brand Name: Berinert

C1 Esterase Inhibitor (Human) is used for:

Treating stomach or facial attacks in certain patients with hereditary angioedema (HAE). It may also be used for other conditions as determined by your doctor.

C1 Esterase Inhibitor (Human) is a C1 esterase inhibitor (human). It works by regulating the clotting and inflammatory reactions that can lead to local tissue swelling (angioedema).

Do NOT use C1 Esterase Inhibitor (Human) if:

  • you are allergic to any ingredient in C1 Esterase Inhibitor (Human) or have had a severe allergic reaction (eg, rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness) to C1 Esterase Inhibitor (Human) or another C1 esterase inhibitor

Contact your doctor or health care provider right away if any of these apply to you.

Before using C1 Esterase Inhibitor (Human) :

Some medical conditions may interact with C1 Esterase Inhibitor (Human) . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood clots in your veins or lungs (eg, deep vein thrombosis, pulmonary embolism)

Some MEDICINES MAY INTERACT with C1 Esterase Inhibitor (Human) . However, no specific interactions with C1 Esterase Inhibitor (Human) are known at this time.

Ask your health care provider if C1 Esterase Inhibitor (Human) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use C1 Esterase Inhibitor (Human) :

Use C1 Esterase Inhibitor (Human) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with C1 Esterase Inhibitor (Human) . Talk to your pharmacist if you have questions about this information.
  • C1 Esterase Inhibitor (Human) is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using C1 Esterase Inhibitor (Human) at home, a health care provider will teach you how to use it. Be sure you understand how to use C1 Esterase Inhibitor (Human) . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use C1 Esterase Inhibitor (Human) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • This product must be used within 8 hours after mixing.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of C1 Esterase Inhibitor (Human) , contact your doctor right away.

Ask your health care provider any questions you may have about how to use C1 Esterase Inhibitor (Human) .

Important safety information:

  • C1 Esterase Inhibitor (Human) may contain albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used C1 Esterase Inhibitor (Human) .
  • Tell your doctor or dentist that you take C1 Esterase Inhibitor (Human) before you receive any medical or dental care, emergency care, or surgery.
  • C1 Esterase Inhibitor (Human) should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if C1 Esterase Inhibitor (Human) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using C1 Esterase Inhibitor (Human) while you are pregnant. It is not known if C1 Esterase Inhibitor (Human) is found in breast milk. If you are or will be breast-feeding while you use C1 Esterase Inhibitor (Human) , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of C1 Esterase Inhibitor (Human) :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; mild injection-site pain or redness; muscle spasms; nausea, stomach pain, or vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bluish color of the lips and gums; calf pain, swelling, or redness; changes in consciousness, speech, or vision; chest pain; dark urine; fainting; fast heartbeat; fatigue; fever or chills; loss of muscle control or muscle weakness on one side of the body; numbness or tingling; severe nausea or stomach pain; severe or persistent headache; severe or persistent injection-site pain or redness; shortness of breath or trouble breathing; swelling or pain in the arms, legs, or stomach; weakness; wheezing; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately. Symptoms may include calf pain, swelling, or redness; shortness of breath or trouble breathing.

Proper storage of C1 Esterase Inhibitor (Human) :

C1 Esterase Inhibitor (Human) is usually handled and stored by a health care provider. If you are using C1 Esterase Inhibitor (Human) at home, store C1 Esterase Inhibitor (Human) as directed by your pharmacist or health care provide. Keep C1 Esterase Inhibitor (Human) out of the reach of children and away from pets.

General information:

  • If you have any questions about C1 Esterase Inhibitor (Human) , please talk with your doctor, pharmacist, or other health care provider.
  • C1 Esterase Inhibitor (Human) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about C1 Esterase Inhibitor (Human) . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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