Severe allergic reactions have occurred immediately following doses of Abarelix , including the first dose. The risk of allergic reaction appears to increase with additional doses. You will be monitored for any sign of an allergic reaction for at least 30 minutes following each dose of medicine. Abarelix is only for use in men when other treatments have failed or are not appropriate and the patient has refused castration. In addition, Abarelix is used when the cancer has spread to the bone, causing severe pain requiring regular doses of narcotics for pain-control, when the risk of neurological problems exists because of the cancer, or when urinary tract problems have resulted from the cancer. The effectiveness of Abarelix to suppress the level of testosterone in the blood decreases with continued use in some patients. Measurement of testosterone levels at certain times during treatment should be done to monitor the continued effectiveness of Abarelix .
Treating symptoms of advanced prostate cancer and certain conditions as determined by your doctor.
Abarelix is a gonadotropin releasing-hormone (GnRH) antagonist. It works by reducing the amount of a hormone called testosterone. Testosterone is involved in the growth of most prostate cancers.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Abarelix . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Abarelix . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Abarelix may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Abarelix as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Abarelix .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Back pain; breast enlargement; breast or nipple pain or tenderness; constipation; diarrhea; dizziness; general pain; headache; hot flashes; nausea; pain, swelling, or redness at the injection site; sleep problems; tiredness; upper respiratory tract infection.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; lightheadedness; fainting; warmth; redness; swelling of the mouth, face, eyelids, lips, tongue, or throat); change in heart rate; cough; dark urine; difficulty or pain when going to the bathroom; fainting; fever; frequently needing to go to the bathroom; pale stools; shortness of breath; stomach pain; swelling of the hands, legs, or feet; unusual tiredness; yellowing of eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Abarelix :
Store the unmixed medicine at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Abarelix has no preservative and must be used within 1 hour of mixing. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Abarelix out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Abarelix . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.