Class Name: carbonic anhydrase inhibitor (Oral route, Parenteral route)
Commonly used brand name(s):
In the U.S.
Available Dosage Forms:
Carbonic anhydrase inhibitors are used to treat glaucoma. Acetazolamide is also used as an anticonvulsant to control certain seizures in the treatment of epilepsy. It is also sometimes used to prevent or lessen some effects in mountain climbers who climb to high altitudes, and to treat other conditions as determined by your doctor.
These medicines are available only with your doctor's prescription.
Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of carbonic anhydrase inhibitors in children with use in other age groups, these medicines are not expected to cause different side effects or problems in children than they do in adults.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of carbonic anhydrase inhibitors in the elderly with use in other age groups, these medicines are not expected to cause different side effects or problems in older people than they do in younger adults.
Carbonic anhydrase inhibitors have not been studied in pregnant women. However, studies in animals have shown that carbonic anhydrase inhibitors cause birth defects. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.
Carbonic anhydrase inhibitors may pass into the breast milk. These medicines are not recommended during breast-feeding, because they may cause unwanted effects in nursing babies. It may be necessary for you to use another medicine or to stop breast-feeding during treatment. Be sure you have discussed this with your doctor.
Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:
Take this medicine only as directed. Do not take more of it and do not take it more often than your doctor ordered. To do so may increase the chance of side effects without increasing the effectiveness of this medicine.
This medicine may be taken with meals to lessen the chance of stomach upset. However, if stomach upset (nausea or vomiting) continues, check with your doctor.
This medicine may cause an increase in the amount of urine or in your frequency of urination. If you continue to take the medicine every day, these effects should lessen or stop. To keep the increase in urine from affecting your nighttime sleep:
However, it is best to plan your dose or doses according to a schedule that will least affect your personal activities and sleep. Ask your health care professional to help you plan the best time to take this medicine.
The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Keep out of the reach of children.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not keep outdated medicine or medicine no longer needed.
This medicine may cause some people to feel drowsy, dizzy, lightheaded, or more tired than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.
It is important that your doctor check your progress at regular visits. Your doctor may want to do certain tests to see if the medicine is working properly or to see if certain side effects may be occurring without your knowing it.
This medicine may cause a loss of potassium from your body. To help prevent this, your doctor may want you to eat or drink foods that have a high potassium content (for example, orange or other citrus fruit juices) or take a potassium supplement. It is very important to follow these directions. Also, it is important not to change your diet on your own. This is more important if you are already on a special diet (as for diabetes) or if you are taking a potassium supplement. Extra potassium may not be necessary and, in some cases, too much potassium could be harmful.
For diabetic patients:
Your doctor may want you to increase the amount of fluids you drink while you are taking this medicine. This is to prevent kidney stones. However, do not increase the amount of fluids you drink without first checking with your doctor.
For patients taking acetazolamide as an anticonvulsant:
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:Rare
Check with your doctor as soon as possible if any of the following side effects occur:More common
Also, check with your doctor if you have any changes in your vision (especially problems with seeing faraway objects) when you first begin taking this medicine.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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