Generic Name: bicalutamide (bye ka LOO ta mide)Brand Names: Casodex
Bicalutamide is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones).
Bicalutamide is used together with another hormone to treat prostate cancer.
Bicalutamide may also be used for purposes other than those listed in this medication guide.
Your doctor may occasionally change your bicalutamide dose to make sure you get the best results from this medication. Do not stop taking bicalutamide without your doctor's advice. If you stop your treatment suddenly, your condition may become worse.
To be sure this medication is helping your condition and is not causing harmful effects, your prostate and liver function will need to be checked with blood tests on a regular basis. Do not miss any scheduled appointments.
Call your doctor at once if you have a serious side effect such as chest pain, shortness of breath, swelling, blood in your urine, or stomach pain with loss of appetite, dark urine, and yellowing of your skin or eyes.
Bicalutamide should never be taken by a woman or a child. Although bicalutamide is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy.Before taking this medication, tell your doctor if you have liver disease, diabetes, or any other serious illness. You may not be able to take bicalutamide, or you may need a dose adjustment or special tests during treatment.
Although bicalutamide is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy.Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Bicalutamide is given as part of a combination prostate cancer treatment with another medication called a luteinizing (LOO-tee-in-ize-ing) hormone-releasing hormone, or LHRH. This medication prevents the testicles from producing testosterone.Bicalutamide is usually taken once per day in the morning or evening. You may take the medicine with or without food. Try to take the medication at the same time each day.
LHRH is given as an injection or a tiny implant injected through a needle under the skin around your navel. LHRH injections are given at intervals such as once every 4 weeks. Follow your doctor's instructions.
You should not start taking bicalutamide until you have received the LHRH injection prescribed as part of your treatment.Your doctor may occasionally change your bicalutamide dose to make sure you get the best results from this medication. Do not stop taking bicalutamide without your doctor's advice. If you stop your treatment suddenly, your condition may become worse.
To be sure this medication is helping your condition and is not causing harmful effects, your prostate and liver function will need to be checked with blood tests on a regular basis. Do not miss any scheduled appointments.
Store bicalutamide at room temperature away from moisture and heat.See also: Casodex dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
Call your doctor for instructions if you miss an appointment for your LHRH injection.
An overdose of bicalutamide is not expected to produce life-threatening symptoms.
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using bicalutamide.
chest pain, cough or trouble breathing;
feeling short of breath, even with mild exertion;
swelling in your hands or feet;
fever, chills, body aches, flu symptoms;
pale skin, easy bruising or bleeding;
blood in your urine; or
nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
hot flashes;
breast pain or swelling;
weakness, dizziness;
back pain, pelvic pain, joint or muscle pain;
increased nighttime urination;
upset stomach, vomiting, diarrhea or constipation;
weight changes;
impotence, loss of interest in sex, or trouble having an orgasm;
dizziness, headache; or
sore throat, runny nose or other cold symptoms.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking this medication, tell your doctor if you are taking a blood thinner such as warfarin (Coumadin).
There may be other medicines that can interact with bicalutamide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.