CeeNU Generic Name: Lomustine
(CCNU) (loe-MUS-teen)Brand Name:
CeeNU is usually taken as a single dose only once every 6 weeks. Do NOT take a dose of CeeNU more than once within a 6-week period without first talking with your doctor.
CeeNU often decreases bone marrow function and lowers the number of white blood cells and platelets in your blood. This may increase your risk for severe infection or bleeding problems. The risk is greater if you take CeeNU more often than once every 6 weeks, take it in high doses, or take it for a long period of time. Tell your doctor right away if you experience symptoms such as persistent fever or sore throat, unusual bruising or bleeding, or unusual fatigue.
You will need to have blood tests every week for at least 6 weeks after each single dose of CeeNU . Your doctor may change your dose of CeeNU based on these tests.
CeeNU is used for:
Treating certain types of cancer.
CeeNU is an alkylating agent used to treat cancer. It stops or slows the growth or spread of certain cancer cells by interfering with their reproduction.
Do NOT use CeeNU if:
- you are allergic to any ingredient in CeeNU
- you have taken a dose of CeeNU within the past 6 weeks, unless your doctor tells you otherwise
Contact your doctor or health care provider right away if any of these apply to you.
Before using CeeNU :
Some medical conditions may interact with CeeNU . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of bone marrow, heart, lung, breathing, liver, or kidney problems
- if you have a bacterial, fungal, or viral infection (eg, shingles, chickenpox)
- if you are undergoing radiation therapy
Some MEDICINES MAY INTERACT with CeeNU . Tell your health care provider if you are taking any other medicines, especially any of the following:
- Cimetidine because the risk of serious bone marrow problems may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if CeeNU may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use CeeNU :
Use CeeNU as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- CeeNU is usually taken as a single dose only once every 6 weeks. You may receive 2 or more types or colors of capsules. Be sure you understand exactly how much of CeeNU to take and how often you should take it. Ask your doctor or pharmacist if you have any questions.
- Take CeeNU by mouth with or without food. Taking it on an empty stomach may reduce the risk of nausea and vomiting.
- Wear gloves when you handle CeeNU to decrease the risk of getting it on your skin or on other items.
- If you miss a dose of CeeNU , contact your doctor immediately.
Ask your health care provider any questions you may have about how to use CeeNU .
Important safety information:
- Do NOT take more than the prescribed dose or take CeeNU more often than once every 6 weeks without checking with your doctor. The risk of severe and sometimes fatal bone marrow problems may be greater if you take CeeNU in high doses or more often than once every 6 weeks.
- Nausea, vomiting, and loss of appetite are common with CeeNU . Ask your doctor or pharmacist for ways to decrease these effects if they occur. Nausea and vomiting usually go away in less than 24 hours. Loss of appetite may last for several days.
- CeeNU may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- CeeNU may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Talk with your doctor before you have any vaccines while you are taking CeeNU .
- Long-term use of CeeNU may increase the risk of developing a second cancer. Discuss any questions or concerns with your doctor.
- Lab tests, including liver, kidney, and lung function and complete blood cell counts, may be performed while you use CeeNU and for 6 weeks or more after you take your last dose. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use CeeNU with caution in the ELDERLY; they may be more sensitive to its effects.
- Caution is advised when using CeeNU in CHILDREN; they may be more sensitive to its effects, especially certain lung problems (pulmonary fibrosis).
- PREGNANCY and BREAST-FEEDING: CeeNU has been shown to cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using CeeNU while you are pregnant. It is not known if CeeNU is found in breast milk. Do not breast-feed while taking CeeNU .
Possible side effects of CeeNU :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Loss of appetite; nausea; occasional hair loss; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blindness; chest pain; chills; confusion or disorientation; decreased amount of urine; dry cough; fever; shortness of breath; sore throat; sores on your mouth or lips; swelling of feet or lower legs; trouble speaking; trouble walking or keeping your balance; unusual bleeding or bruising; unusual fatigue or weakness; vision changes; yellowing of skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of CeeNU :
Store CeeNU at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Avoid temperatures higher than 104 degrees F (40 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep CeeNU out of the reach of children and away from pets.
- If you have any questions about CeeNU , please talk with your doctor, pharmacist, or other health care provider.
- CeeNU is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about CeeNU . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
- CeeNU Prescribing Information (FDA)
- Lomustine Professional Patient Advice (Wolters Kluwer)
- Ceenu Concise Consumer Information (Cerner Multum)
- Ceenu Advanced Consumer (Micromedex) - Includes Dosage Information