Serious and sometimes fatal reactions have occurred in patients receiving Cetuximab . Many of the reactions have occurred during the first dose. If you develop symptoms such as sudden trouble breathing; hoarseness; wheezing; hives; itching; fever; chills; severe dizziness; fainting; swelling of the mouth, face, lips, or tongue; chest pain or tightness; or numbness of an arm or leg, seek immediate medical attention.
The risk of heart attack or sudden death may be increased in patients who receive Cetuximab along with radiation to treat certain types of cancer of the head and neck. Be sure to tell your doctor if you have heart blood vessel problems, heart failure, or an irregular heartbeat. Lab tests, including blood electrolytes, may be performed while you use Cetuximab and for a period of time after you finish Cetuximab .
Treating certain types of head, neck, and colorectal cancer. Cetuximab may be used alone or along with radiation treatments or other medicines. It may also be used for other conditions as determined by your doctor.
Cetuximab is a monoclonal antibody. It works by blocking a certain growth factor. This helps to reduce the growth and survival of certain types of cancer cells.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Cetuximab . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Cetuximab . However, no specific interactions with Cetuximab are known at this time.
Ask your health care provider if Cetuximab may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Cetuximab as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Cetuximab .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Changes in fingernails or toenails; constipation; cough; diarrhea; dry mouth; dry skin; eye redness or irritation; general body discomfort; headache; indigestion; mild acne; nausea; pain, swelling, or redness at the injection site; sore throat; stomach pain or upset; tiredness; trouble sleeping; vomiting; weakness; weight loss.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breathing problems or shortness of breath; change in the amount of urine produced; chest pain; confusion; eye or eyelid redness, swelling, or irritation; fainting; fever, chills, or persistent sore throat; hoarseness; increased abnormal hair growth; mental or mood changes (eg, anxiety, depression); numbness of an arm or leg; peeling, redness, cracking, or oozing of the skin; severe or persistent acne; severe or persistent dizziness or headache; severe or persistent stomach pain, nausea, or vomiting; severe or persistent tiredness or weakness; sores on the lips or in the mouth; swelling of the hands, legs, or feet; trouble swallowing; vision changes; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Cetuximab :
Cetuximab is usually handled and stored by a health care provider. If you are using Cetuximab at home, store Cetuximab as directed by your pharmacist or health care provider.
This information is a summary only. It does not contain all information about Cetuximab . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.